Figure 1. Pleocytosis (shown here) is an increased cell count — particularly an increase in white blood cell (WBC) count — in a bodily fluid such as cerebrospinal fluid (CSF).

Neutrophilic Pleocytosis is Connected to Viral CNS Infections

By Caleb Sooknanan ’20 Viral central nervous system (CNS) infections are often associated with cerebrospinal fluid (CSF) lymphocytic pleocytosis, or an increase in the fluid’s white blood cell count. However, these infections are also connected to neutrophilic pleocytosis, an increase in the fluid’s neutrophil count. The clinical and prognostic significance of CSF neutrophilic pleocytosis remains…

Figure 1: Shown here is an example of Scopulariopsis, a genus of fungi capable of living in the absence of soil, air, plant debris, and dung. A new species of this fungi was recently discovered in cotton plants in Hangzhou, China.

Combination Therapies Reduce Treg Functions in CHC Patients

by Caleb Sooknanan ’20 Regulatory T-Cells, or Tregs, are important contributors to the development of chronic hepatitis C (CHC) infections in patients. Oral antiviral agents are the most common treatments for CHC infections in most Western countries, while pegylated interferon (PEG-IFN) treatment is the standard therapy in many Asian countries. PEG-IFNs are interferons that attach…

Figure 1: Researchers at the Yokohama City University Graduate School of Medicine in Japan used computational fluid dynamics (shown) to analyze the flow distribution of anticancer agent into the branches of the external carotid artery during intra-arterial chemotherapy.

Computational Fluid Dynamics Can Be Used to Treat Oral Cancer

by Caleb Sooknanan ’20 Surgical procedures have often been used to treat oral cancer. However, these procedures can cause oral dysfunction — often in the form of speech and breathing difficulties — and thereby harm respiratory organs. To preserve organ function, intra-arterial chemotherapy (IAC) has become a valuable form of treatment. IAC releases more anticancer…

Figure 1: Pegylated-interferon (PEG-IFN) treatment is the standard therapy for chronic hepatitis C in Asian countries; it is sometimes performed as part of a combination therapy with ribavirin (RBV), but more research is needed to understand how Treg function is affected in patients.

New Species of Fungi Discovered in Chinese Cotton Plants

by Caleb Sooknanan ’20 Dr. Xiao-Lin Li and researchers at Zhejiang University in China recently discovered a new fungal species, now identified as Scopulariopsis gossypii. The species was found in the vascular bundles of cotton plants infected by Verticillium dahlia, a pathogen of economic importance throughout the city of Hangzhou. Scientists have already associated the…