Inducing Tumor Cell Death by RIG-I: The Future of Breast Cancer?

By Riya Gandhi ‘22 In recent years cancer therapy – especially cancer immunotherapy – has gained momentum and scientists’ interest has turned to immune checkpoint inhibitors (ICIs). ICIs aid in the suppression of checkpoint receptors to produce powerful immune responses against tumors. Although such a procedure is gaining momentum in clinical settings, much research must…

Disruption of GABPβ1L Reverses Immortality of Glioblastoma Cells

By Riya Gandhi ‘22 Researchers in the Department of Neurological Surgery at the University of California have made a progressive discovery regarding tumor cell immortality, especially in brain-related cancers such as glioblastoma, which recently claimed the life of Senator John McCain. Their work involved TERT promoter mutations, which are responsible for activating telomerase and thereby…