The effect of diabetes on fingernail quality

By Kavindra Sahabir ‘21 In our current public understanding, Type 2 diabetes (T2D) is associated with the need for sugar-free foods and blood sugar monitors. Beyond a high blood sugar level however, it also causes chronic degradation and damage to nerves, joints, and other bodily tissues. A study done by Dr. Silhota and team endeavored to determine whether the fingernail could be a useful site … Continue reading The effect of diabetes on fingernail quality

Inducing Leukemia Cell Death Through the Inhibition of Amino Acids

By Riya Gandhi ‘22 Thanks to chemotherapy, acute myeloid leukemia (AML) is not the most fatal kind of cancer. However, the same chemotherapy that treats the disease may also revitalize leukemia stem cell populations, thereby increasing the probability of relapse. As such, scientists are still actively researching alternative treatments and cures. Most recently, researchers looked into the importance of amino acids for preventing the growth … Continue reading Inducing Leukemia Cell Death Through the Inhibition of Amino Acids

Expression of Transcription Factor TP63 Reprograms Squamous Pancreatic Ductal Adenocarcinoma Cells

By Riya Gandhi ‘22 Although pancreatic cancer is not the most common type of cancer, the prognosis for those diagnosed with the disease is very poor. Much like any other cancer, pancreatic cancer develops when cells in the organ multiply at an uncontrollable rate. Pancreatic ductal adenocarcinoma (PDA), the most common type of pancreatic cancer, garnered the attention of researchers at Cold Spring Harbor Laboratory … Continue reading Expression of Transcription Factor TP63 Reprograms Squamous Pancreatic Ductal Adenocarcinoma Cells

Infectious Diseases may Cause Major Depressive Disorder

By: Marianna Catege Depression may actually be infectious, according to Dr. Turhan Canli, the Associate Professor of Psychology and Radiology at Stony Brook University. His claim puts Major Depressive Disorder (MDD) in a new light, one that suggests it can be caused by parasitc bacterial or viral infections. In this highly prevalent disease, with roughly 7 percent of the U.S. population developing MDD, symptoms can … Continue reading Infectious Diseases may Cause Major Depressive Disorder

Aristolochic Acid and Chemically Modified Curcumin: an Overview

By Michael Baxter Dr. Francis Johnson received his Ph. D. from Glasgow University in Scotland in 1954 and went on to become a postdoctoral fellow at Boston University until 1957. He worked at the Dow Eastern Research Laboratory before coming to Stony Brook University in 1973, where he became the founding vice-chairman of the Department of Pharmacological Sciences [1]. Currently Dr. Johnson is part of … Continue reading Aristolochic Acid and Chemically Modified Curcumin: an Overview

Aristolochic Acid, used in herbal remedies, linked to urothelial cancers and neuropathic diseases

By Katherine Maiorisi Dr. Grollman of Stony Brook University was honored in 2011 with the Environmental Mutagen Society (EMS) award for his work on aristolochic acid (AA) and its relation to cancer and neuropathy [1]. Throughout the past fifty years studies have been done on the effect of environmental agents on neuropathy. Aristolochia poisoning was first proposed in 1969 by Ivi´c, but was disregarded, until … Continue reading Aristolochic Acid, used in herbal remedies, linked to urothelial cancers and neuropathic diseases