Figure 1: This is an image of a typical asthma inhaler. With further development of MPPs, the drugs within these inhalers will be more effective than they are currently.

Nanoparticle Drug Delivery

Richard Liang 18’ Mucoadhesive particles (MAPs) are used as the primary method of pulmonary drug delivery since it was believed that they increase drug duration within the lungs. MAPs act by sticking to the mucus layers and are used to treat a variety of illnesses including asthma, cystic fibrosis and lung cancer. However, administered MAPs…

Photocurable Bioinks and 3D-Printed Hydrophilic Drugs

  By Caleb Sooknanan ’20 Pharmaceutical dosages are often defined as the amount of active pharmaceutical ingredient (API) that has a therapeutic effect in the most patients. Using such a generalized method does not account for variations in patient genomic and pathophysiological status, leading to potential negative side-effects. Personalized medicine intends to provide patients with…

Figure 1. Mammalian brains can be influenced by non-genetic and Allele-Specific expression

Sending Your Grandparents to University Increases Cognitive Reserve: The Tasmanian Healthy Brain Project

By Ericka Berman   One way to decrease the likelihood of Alzheimer’s disease is by increasing cognitive reserves (CR). Research supports the idea that education, intelligence, and cognitively stimulating activities modify the risk for dementia. CR is a theoretical construct, so it is measured indirectly. Dr. Megan Lenehan and her team of researchers used data from…

Blunted Neural Response to Rewards as a Prospective Predictor of the Development of Depression in Adolescent Girls

    By Ericka Berman Previous studies have shown that during adolescence, rates of depression increase markedly, and girls tend to have rates of depression twice as high as boys. Depressed adults were also shown to exhibit a decreased behavioral response to a reward and less brain activity in regions associated with reward processing in…