Fibrinogen Plays a Neurodegenerative Role in Alzheimer’s Disease

By Natalie Lo ‘21 Alzheimer’s Disease (AD) is characterized by the formation of β-amyloid plaques Aβ, microglial activation, and inflammation in the brain. Microglia are immune cells found in the central nervous system (CNS). In AD, the blood-brain barrier is disrupted, which leads to bleeding, vascular damage, and an increase in blood proteins. Currently, there is an unknown relationship between vascular dysfunction, proteins like fibrinogen … Continue reading Fibrinogen Plays a Neurodegenerative Role in Alzheimer’s Disease