Scientists Are Growing Human Brains in Mice

By Marcia-Ruth Ndege ‘21 Human pluripotent stem cells can differentiate into nearly any cell in the human body. Recently, geneticist Abed AlFatah Mansour and other scientists from the Salk Institute for Biological Studies used them to build human brains in mice. The differentiation of human pluripotent stem cells gave rise to small brain-like structures known…

Student Researcher Interview with Dan Monessa

Interviewer: Benjamin Kerner Interviewed: Dan Monessa B: The first question is really just for the record, so what is your name, major, and what is your department of research? D: Sure, my name is Dan Monessa, I am a biochemistry major and the department of research I was in, was the department of Gastroenterology and…

Brain Cancer and SENP1Silencing

By Daniel Walocha ‘19 Astrocytomas are the most common type of glioma and contain the most detrimental subtype of brain cancers, glioblastoma multiforme. Astrocytomas affect the astrocytes in the brain, which make up the blood-brain barrier. Xia et al. from Purdue University looked to study the effect of SUMO-specific protease 1 (SENP1) knockout in cell…

Urethral Carcinoma

By Daniel Walocha ‘19 Urethral carcinomas are not understood well enough to be mapped out for clinical and pathologic description. The cellular shape and function has been described to be squamous (flattened) and aggressive due to its ability to metastasize to distant organs. The mean survival and follow-up with patients offer a correlation between urethral…

TIGAR Protein Associated Survival in Viral Carcinogenesis

By Daniel Walocha ‘19 Oncogene overexpression will lead to cancer phenotypes that can accumulate cytotoxic metabolites, reactive oxygen species (ROS), and other apoptosis-inducing factors in the cell. It is therefore necessary for the cancerous cell to eliminate the apoptosis-inducing factors or suppress apoptosis altogether. Dr. Megan Romeo et al. from Richland College has detected a…

Habitat Creation and Woodland Bird Populations

By Fatin Chowdhury ‘19 Many are aware of the need for conservation in ecologically vulnerable locations, but scientists continue to seek to clarify the details surrounding conservation logistics. A study led by Dr. Robin Whytock at the University of Sterling examined differences in local and landscape habitat creation for bird communities within the woodland forests…

Visualizing the Impacts of Age and Disease on the Brain

By Fatin Chowdhury ‘19 Alzheimer’s disease (AD), a common neurodegenerative disorder, has previously been found to increase atrophy rate of the hippocampus, an area of the brain associated with learning and memory. In relation to this issue, Dr. Daniel H. Adler and researchers from the University of Pennsylvania recently examined specific structural details of the…