Graphitic Electro-catalytic Fuel Cells

By Meenu Johnkutty ‘21 For decades, climate scientists have touted wind, solar, and nuclear energy as alternatives to fossil fuels, which, due to their affordability, nonetheless remain an attractive avenue for big oil companies. Recent studies have demonstrated that fuel cells, electrochemical cells that convert hydrogen into electricity, have potential to replace current energy sources.…

Mucopolysaccharidoses Treatment with Gene Therapy

By Daniel Walocha ‘19 Muscopolysaccharidoses (MPS) is a lysosomal storage disorder which results from a deficiency of lysosomal enzymes. The lack of enzymes causes an accumulation of glycosaminoglycans that can lead to severe symptoms including heart disease, nervous system damage, and skeletal dysplasia. Enzyme replacement therapies, hematopoietic stem cell transplantation, and substrate reduction therapy are…

Nanomaterial’s Potential in Cancer Immunotherapy

By Daniel Walocha ‘19 Immunotherapy is a promising therapy that has potential since it uses the patient’s own immune system to kill cancer cells. This unique quality that is not usually present in radiation or chemotherapy has promise in that it can present a durable treatment that limits metastasis and future recurrences. Since cancer cells…

FOXO Proteins Role in Cancer Pathways

By Daniel Walocha ‘19 FOXO proteins have previously been established as transcription factors in genes controlling mitogenic cell growth, metabolism, and proliferation. They contain a common sequence, the forkhead box, which encodes for a string of 80-100 amino acids which form a DNA-binding motif. Though, the specific cancer pathways and crosstalk among the signaling proteins…

The Genetics Behind Sleep Duration

By: Meenu Johnkutty ’21 The need to sleep is one of health and medicine’s biggest paradoxes. Though we spend nearly a third of our lives asleep, little is really known about this process. According to the American Academy of Sleep Medicine, over 30 to 35% of the population suffers from insomnia, which is characterized by…