Improved Body Composition After Testosterone Treatment in Young Male Cancer Survivors

Priyanshi Patel ’22 Young male cancer survivors have low testosterone levels compared to those of  healthy populations. Long term effects of low testosterone involve endocrine disorders that affect up to 50% of adult childhood cancer survivors, and younger survivors are often unsure as to whether they would benefit from testosterone treatment. A study was conducted in the United Kingdom on secondary hospital outpatients.. The study … Continue reading Improved Body Composition After Testosterone Treatment in Young Male Cancer Survivors

Growth Factor Induces Methylation Changes in Lung Fibroblasts

Priyanshi Patel ’22 Idiopathic Pulmonary Fibrosis (IPF) is an irreversible, chronic, and lethal disease of unknown etiology. IPF is characterized by excessive deposition of extracellular matrix (ECM), which is secreted mainly by activated fibroblasts under certain stimuli. Recent studies have evaluated alterations with DNA methylation as a collective driver of IPF. Few studies explore global DNA methylation in lung fibrosis, but none focused on transforming … Continue reading Growth Factor Induces Methylation Changes in Lung Fibroblasts

Can a Reduction in Carbohydrate Consumption Produce Adverse Effects?

Jorge Pincay ’20 Low carbohydrate  diets (LCD) have been adopted by many patients as a means of battling diseases such as cancer, diabetes, obesity, and many other metabolic disorders. This type of diet is even widely used by the general population for maintaining and/or losing weight. However, not many studies  have investigated the adverse health effects that may result from a sudden halt in carbohydrates … Continue reading Can a Reduction in Carbohydrate Consumption Produce Adverse Effects?

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Announcement: Applications

Staff and writer applications are officially open for the spring semester! Staff Application: https://docs.google.com/forms/d/e/1FAIpQLSfaC4FQUBAl-1eBd1ZQSM27XBOEX33_3dc6i2rJTadldV0Erw/viewform Writer Application: https://docs.google.com/forms/d/e/1FAIpQLSfLFHh_fJ48envx5QU_IGMFpxqBi5PglONQJ1eeOpwtg_Wt8w/viewform?usp=sf_link Note: You will need to log in using your Stony Brook Google account upon clicking the above links. Writers are highly preferred. Writers will be allowed to write about any topic, so long as it pertains to the journal theme – though exceptions to the theme may be … Continue reading Announcement: Applications

Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

Jorge Pincay ’20 Phosphoglycerate mutase 1 (PGAM1) is a gene known to promote rapid tumor growth and invasiveness in several cancers, including non-small cell lung cancer (NSCLC). PGAM1 encodes for an enzyme that catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate in the glycolytic pathway,  a compound that coordinates anabolic biosynthesis. In many forms of cancer, including NSCLC, urothelial bladder cancer, and hepatocellular carcinoma, upregulation of … Continue reading Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

New Chemical Compound to Reduce the Adverse Side Effects of Neural Implants

Jorge Pincay ’20 Over the years research in neuroscience has led to the development of brain implants, called microelectrodes that can help restore essential motor and sensory functions. This technology has become beneficial for those that suffer from head injury and neurodegenerative disease. The limitations of this technology lie within the immunological response that comes about shortly after implantation. This immune response, which is governed … Continue reading New Chemical Compound to Reduce the Adverse Side Effects of Neural Implants

Ecological Dynamics of Coastal Plants, Birds, and Herbivores

Fatin Chowdhury ’20 In a recent paper, scientists from the University of Irvine examined the resistance of shrub plants to herbivory, as enabled by plant morphology or the presence of avian species. The scientists studied both direct and indirect defenses in nature and assessed these mechanisms in the context of energetic trade-offs. Characteristics that were already known to directly lower the success rate of herbivory … Continue reading Ecological Dynamics of Coastal Plants, Birds, and Herbivores

Interactions between a Tree Exudate and a Loquat-Seed Starch

Fatin Chowdhury ’20 As naturally derived ingredients become more sought after in manufacturing and other areas, the science behind biodegradable material continues to expand. Recently, in order to better understand the chemical dynamics of different ingredients in biomaterials and explore the possibility of developing an edible film, a pair of scientists located in South Korea investigated the interactions of a tree-based gum with loquat-seed derived … Continue reading Interactions between a Tree Exudate and a Loquat-Seed Starch

Common Fungi May Drive Pancreatic Cancer

Nicole Zhao ’20 Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide and occurs more frequently in developed countries (1). What makes pancreatic cancer even more alarming is that patients seldom exhibit symptoms until an advanced stage of the disease when little can be done for them (1). Therefore, techniques in early detection and risk assessment are crucial in the prognosis of a … Continue reading Common Fungi May Drive Pancreatic Cancer

Neurons that Help Us Forget

Nicole Zhao ’20 Imagine having the ability to never forget. This would come in handy if one needed to memorize a textbook or lecture slides for an exam. However, being able to remember every single moment of your life in snapshots does have its drawbacks. This is exactly what happened to a man known as subject S. who was known for his unforgettable memory in … Continue reading Neurons that Help Us Forget