Analysis of Female Pupillary Response as a Potential Reflection of “Cuteness”

Ayesha Azeem ’23 Observing something “cute” facilitates communication, as perceiving cuteness narrows perceptual attention and makes it difficult to focus on peripheral vision. Previous research has indicated that female reproductive hormones allow women to be more sensitive and attuned to perceiving cuteness. Because women have historically played the role of primary caregiver, evolutionary psychology suggests that cuteness motivates people to raise a child, which may … Continue reading Analysis of Female Pupillary Response as a Potential Reflection of “Cuteness”

How the Motor Cortex Plays a Role in Parkinson’s Disease

Ayesha Azeem ’23 Parkinson’s Disease is a brain disorder that leads to shaking, stiffness, and difficulty with walking and balance. The symptoms gradually begin and get progressively worse over time. Although neuroscientists understand the role of neuron and dopamine loss in Parkison’s Disease, little is known about how dopaminergic modulation affects brain regions that are involved in the control of voluntary movement. In the primary … Continue reading How the Motor Cortex Plays a Role in Parkinson’s Disease

Similar but Different: The Potential Role of Spatial Differentiation in Memory Retrieval

Robyn Rutgers ’24 Researchers have long been interested in establishing how the brain remembers spatial environments and avoids confusion in similar environments, such as in a new supermarket. A recent study from University of Arizona researchers investigates how the processes of spatial memory retrieval are implemented in the brain and how the brain differentiates memory representations that involve overlapping features. The study recruited 27 participants … Continue reading Similar but Different: The Potential Role of Spatial Differentiation in Memory Retrieval

Glial Cells May Shape Brain Tumor Microenvironments

Alex Moir ’23 Glial cells, located in the central nervous system (CNS), support neurons by clearing extracellular waste and mounting an immune response against potential pathogens. Glioma are tumors occurring in the CNS that originate from these glial cells. As glioma tumors progress and become more aggressive, they invade surrounding tissue and develop a hospitable tumor microenvironment (TME). Two types of resident CNS immune cells, … Continue reading Glial Cells May Shape Brain Tumor Microenvironments

The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

Alex Moir ’23 Human herpesvirus 6B (HHV-6B) is one of the most prevalent herpesviruses amongst tested populations, with estimates placing worldwide infections near 100%. HHV-6B is neurotropic, establishing a lifelong infection in the brain and entering a period of latency in which replication and spread is inhibited. The activity of HHV-6B and its effects on the brain during latent infection are poorly understood. Examination of … Continue reading The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

NSC-Derived Antibody Proves a Selective NSC Marker

Vignesh Subramanian ’24 Neural stem cells (NSCs) are multipotent cells capable of differentiating into the major types of mature cells in the central nervous system (CNS) – neurons and glia – and giving rise to unlimited generations of those cells. Alongside progenitor cells, which are descended from NSCs and differentiate into specific target cells, NSCs are critical in advancing neurogenesis, the development of neurons from … Continue reading NSC-Derived Antibody Proves a Selective NSC Marker

Brain Imaging May Prevent Obesity and Linked Psychological Behaviors

Sooraj Shah ’24 Obesity rates in the United States, approaching almost 70% for men and 62% for women, are concerning, especially since obesity is associated with several other conditions such as heart attacks and diabetes. While the classic solution is exercise and proper diet maintenance, the ability to predict and prevent obesity has become a topic of research. A study led by Dr. Anat Biegon, … Continue reading Brain Imaging May Prevent Obesity and Linked Psychological Behaviors

How Does the Brain Learn Taste Aversion?

Ayesha Azeem ‘23 The gustatory system is the sensory system that allows humans to perceive the sense of taste, or flavor. Humans are able to perceive different flavors via the taste receptors on taste buds, which can be found on the upper surface of the tongue as well as on the epiglottis. Taste perception depends on the chemical characteristics of the stimulus, as well as … Continue reading How Does the Brain Learn Taste Aversion?

The Correlation Between Urinary Growth Factor and Brain Growth in Relation to Postnatal Development

Sooraj Shah ’24 Premature births occur in nearly 1 in every 10 cases in the United States, which can lead to numerous diverse health effects in the future. Two neurotrophic proteins which are responsible for the survival of neurons, Nerve Growth Factor(NGF) and Brain Derived Neurotrophic Factor(BDNF), are crucial for the development of the peripheral and central nervous systems. NGFs and BDNFs are critical for … Continue reading The Correlation Between Urinary Growth Factor and Brain Growth in Relation to Postnatal Development

Response Inhibition Control in Migraineurs

Wendy Wu ’22 Migraine is a neurological disorder characterized by frequent headaches, particularly prevalent in women. Much research has gone into identifying the causes of migraines with the hope of increasing preventative measures and developing treatment. Although evidence suggests that migraines are caused by an imbalance of cortical excitatory and inhibitory processes, there is little empirical data of actual pathophysiological features underlying response inhibition in … Continue reading Response Inhibition Control in Migraineurs

Creation of Images by Detecting brain activity via Neuroadaptive Generative Modeling

Sooraj Shah ’24 The relationship between humans and technology is one which advanced the world to where it is today. By physically pressing a few buttons, we are able to express our thoughts and ideas onto a digital screen. However, this might not always be the case. Researchers at the University of Helsinki have developed neuroadaptive generative modeling, in which a computer creates a visual … Continue reading Creation of Images by Detecting brain activity via Neuroadaptive Generative Modeling

Effect of Mutation in NMDA Receptor Proteins resulting in Neurological Disorders

Sooraj Shah ’24 Neurological disorders affect 25 million people in the United States, which makes the study of NMDA receptors increasingly important. NMDA receptors are key contributors to regulation of memory and behavior in the human brain. NMDA (N-methyl-D-aspartate) receptor proteins are transmembrane proteins, and are in a subset of Ionotropic glutamate receptors (iGluRs), which contain 4 helices, the most significant of which is the … Continue reading Effect of Mutation in NMDA Receptor Proteins resulting in Neurological Disorders