Genetic factors may be involved in disease risk of early-onset autoimmune thyroid disease

Panayiota Siskos ’23 Autoimmune thyroid diseases, such as Graves’ disease and Hashimoto’s disease, are often characterized by the infiltration of T cells and B cells in the thyroid as well as the production of antibodies specific to thyroid antigens. Genes including human leukocyte antigen (HLA), cytotoxic T lymphocyte-associated factor 4 (CTLA-4), CD40, and protein tyrosine phosphatase-22 (PTPN-22) have been previously associated with susceptibility to autoimmune … Continue reading Genetic factors may be involved in disease risk of early-onset autoimmune thyroid disease

Threatening cues have a larger effect on perception than neutral cues

Panayiota Siskos ’23 The theory of predictive coding states that the brain continuously creates a mental model of the surrounding environment using prior knowledge from memory. This mental model is then used to predict sensory input, such as anticipating a smell, a sound, or a touch.  A group of researchers from Stony Brook University and Columbia University studied the effect of threatening cues on sensory … Continue reading Threatening cues have a larger effect on perception than neutral cues

Application of Trispecific Antibodies to Anticancer Immunotherapy

Ashley Goland ’23 Immunotherapy is a form of cancer treatment that utilizes the body’s own immune system to destroy cancerous tumors and has shown promise in past animal and clinical human trials. For all of its dazzling successes to date, however, immunotherapy is not completely effective for treating the full range of cancer types and patients— yet. Scientists working in Sanofi Research and Development believe … Continue reading Application of Trispecific Antibodies to Anticancer Immunotherapy

Implications of Solar Geoengineering

Ashley Goland ’23 Solar geoengineering is a technology that aims to reflect incoming sunlight away from the Earth to reduce the rise of global temperatures, and one proposed approach is to send aerosols into the atmosphere. Although this method may seem like a quick, relatively cheap way to delay further climate change, the effects it could have upon marine and terrestrial organisms are not yet … Continue reading Implications of Solar Geoengineering

Breeding can Change Dogs’ Brains

Ayesha Azeem ‘23 For centuries, humans have been breeding domestic dogs with the intention of producing specific skill sets needed to improve humans’ lives. For example, purpose-bred dogs can be used for hunting or as service dogs that guide people with disabilities. Dog breeding has been highly controversial lately, since dogs are now seen more as companions rather than workers. In a new study conducted … Continue reading Breeding can Change Dogs’ Brains

Comfort Eating and Cortisol Reactivity

Ayesha Azeem ‘23 “Comfort-eating,” or increased food intake, is one of the most common responses to stressful situations. Cortisol is the body’s main stress hormone that regulates metabolism and the immune response to stressful situations. Cortisol reactivity under stress can predict stress-related eating behavior and how it affects the body mass index (BMI). Based on one’s cortisol reactivity to a stressor, a person may be … Continue reading Comfort Eating and Cortisol Reactivity

Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

Simran Kaur ‘20 Acute respiratory distress syndrome (ARDS) is characterized by the build-up of fluid in the alveoli of the lungs, the main sites of gaseous exchange, causing a lack of oxygen in the body. ARDS is caused by sudden trauma to the lungs, and there currently is no pharmacological treatment for the condition. Researchers in the study sought to determine the efficacy of dexamethasone, … Continue reading Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

Different Types of Anesthesia can Impact Breast Cancer Metastasis.

Priyanshi Patel ‘22 Metastasis refers to the surgical removal of solid tumors and metastasis is the main cause of cancer death. Previously, not much was known about the role anesthetics play in cancer metastasis. Complete surgical removal of solid tumors offers the possibility of a cure and is the basic treatment provided. Despite surgery, recurrent metastasis in vital organs does reoccur and is a major … Continue reading Different Types of Anesthesia can Impact Breast Cancer Metastasis.

Countdown to 2050 to Save the Amazon.

Priyanshi Patel ‘22 The number of fires in the Amazon last year had renewed public concern for the future of the region’s forest biome. The concerns date back to the early 1970s when Brazil made the Transamazon Highway, after which the rate of deforestation increased. One of the principal questions Amazon scientists are asking is, how much deforestation and global climate change can the Amazon’s … Continue reading Countdown to 2050 to Save the Amazon.

Examining the Benefits of Unique Coloration for Male Trinidad Guppies

Fatin Chowdhury ’20 The predisposition of organisms in seeking certain phenotypic traits in mates is an oft-observed aspect of the natural world, with sexual selection being a well-studied phenomenon. However, unique coloration specifically often seems to be more linked to lessened survivability (due to an inability to camouflage in environments), or phenomena such as aposematism, where unique colors serve as a warning for predators. In … Continue reading Examining the Benefits of Unique Coloration for Male Trinidad Guppies