Lymphatic Vessels Can Improve Cognition Relative to Age

Caleb Sooknanan ‘20 Aging is often associated with increased neurological problems among humans, and more research is needed to understand how lymphatic vessels connecting the brain and the immune system affect conditions such as Alzheimer’s disease. Doctor Jonathan Kipnis and researchers from the University of Virginia enhanced the lymphatic vessels of aging mice and significantly…

Scientists Are Growing Human Brains in Mice

By Marcia-Ruth Ndege ‘21 Human pluripotent stem cells can differentiate into nearly any cell in the human body. Recently, geneticist Abed AlFatah Mansour and other scientists from the Salk Institute for Biological Studies used them to build human brains in mice. The differentiation of human pluripotent stem cells gave rise to small brain-like structures known…

Visualizing the Impacts of Age and Disease on the Brain

By Fatin Chowdhury ‘19 Alzheimer’s disease (AD), a common neurodegenerative disorder, has previously been found to increase atrophy rate of the hippocampus, an area of the brain associated with learning and memory. In relation to this issue, Dr. Daniel H. Adler and researchers from the University of Pennsylvania recently examined specific structural details of the…

Using Hunger to Suppress Pain

By Marcia-Ruth Ndege ‘21 Much is known about how the brain communicates needs such as thirst, hunger, pain, and fear. However, little is known about how the brain prioritizes such needs. In the context of pain, researchers must examine both acute and inflammatory pain. Acute pain is a reflexive response, while inflammatory pain is mediated…