Category: General Neuroscience

General Neuroscience

Music to One’s Ears: Familiarity and Music Engagement in People With Parkinson’s Disease

Thumyat Noe ’23 Parkinson’s disease is a brain disorder characterized by loss of dopamine and reduced innervation of neural structures that are responsible for coordination of motor movements. Affected individuals often have difficulty walking and maintaining balance. However, music has been shown to be a helpful external cue that reduces these symptoms. Research shows that exposure to music activates brain regions that are closely related … Continue reading Music to One’s Ears: Familiarity and Music Engagement in People With Parkinson’s Disease

Young Investigators ReviewLeave a comment
General Neuroscience

Compartmental function and modulation of the striatum

Sabah Bari ‘24 The striatum is one of the main input areas of the basal ganglia, a neuronal circuit necessary for voluntary movement control. It is a critical component of motor control, action selection and reward systems within the brain. Almost all elements of the brain’s reward circuit are modulated during social behavior. The striatum has two main efferent pathways. There are 2 main efferent … Continue reading Compartmental function and modulation of the striatum

Young Investigators ReviewLeave a comment
General Neuroscience

Going to College Can Delay Alzheimer’s Disease Onset

Ayesha Azeem ‘23 Alzheimer’s disease is an irreversible brain disorder that progresses to destroy memory and thinking skills until one fails to complete basic tasks. Alzheimer’s most commonly begins to affect people in their mid-60s, and is currently the third leading cause of death for the elderly in the United States (NIH). A recent study conducted by Stony Brook University researchers revealed that attending college … Continue reading Going to College Can Delay Alzheimer’s Disease Onset

Young Investigators ReviewLeave a comment
Brain

Creation of Images by Detecting brain activity via Neuroadaptive Generative Modeling

Sooraj Shah ’24 The relationship between humans and technology is one which advanced the world to where it is today. By physically pressing a few buttons, we are able to express our thoughts and ideas onto a digital screen. However, this might not always be the case. Researchers at the University of Helsinki have developed neuroadaptive generative modeling, in which a computer creates a visual … Continue reading Creation of Images by Detecting brain activity via Neuroadaptive Generative Modeling

Young Investigators ReviewLeave a comment
Neuroscience

Effect of Mutation in NMDA Receptor Proteins resulting in Neurological Disorders

Sooraj Shah ’24 Neurological disorders affect 25 million people in the United States, which makes the study of NMDA receptors increasingly important. NMDA receptors are key contributors to regulation of memory and behavior in the human brain. NMDA (N-methyl-D-aspartate) receptor proteins are transmembrane proteins, and are in a subset of Ionotropic glutamate receptors (iGluRs), which contain 4 helices, the most significant of which is the … Continue reading Effect of Mutation in NMDA Receptor Proteins resulting in Neurological Disorders

Young Investigators ReviewLeave a comment
General Neuroscience

Developmental History Skews Alzheimer’s Diagnosis

Vignesh Subramanian ’24 Alzheimer’s disease (AD) is a neurodegenerative disease that, alongside related dementias, afflicts nearly 50 million people worldwide with incidence rates increasing with age. Alzheimer’s is particularly debilitating in areas of language and memory, contributing to progressive cognitive decline that is frequently diagnosed using neuropsychological tests evaluating recall, visual processing and executive function. Yet while such assessments are meant to ascertain whether patients … Continue reading Developmental History Skews Alzheimer’s Diagnosis

Young Investigators ReviewLeave a comment
General Neuroscience

Fears and How Priming Can Help Overcome Them

Yukta Kulkarni ’22 Some of the most important topics covered by neuroscience research encompass memory retention. This type of research helps explain how much information brains can retain and how easily it is learned. However, does prior learning affect the ability to learn in the future? To answer this, Cole et al. blocked protein-kinase A (PKA) and extracellular signal-related mitogen-activated protein-kinase (ERK/MAPK) within the basolateral … Continue reading Fears and How Priming Can Help Overcome Them

Young Investigators ReviewLeave a comment
General Neuroscience

World Trade Center first responders with PTSD and cognitive impairment at high-risk for developing dementia

Priyanshi Patel ’22 According to two studies presented by Stony Brook University at the Alzheimer’s Association International Conference, World Trade Center (WTC) first responders with signs of cognitive impairment (CI) exhibited neurological abnormalities and anomalies in their blood, which are normally attributed to Alzheimer’s disease patients. The first study investigated MRI results of WTC responders that showed significant gray matter atrophy compared to individuals of … Continue reading World Trade Center first responders with PTSD and cognitive impairment at high-risk for developing dementia

Young Investigators ReviewLeave a comment
General Neuroscience

Effects of distractive and target stimuli on auditory neurons within mice brains

Joyce Chen ’23 Biological organisms are naturally stimulated by their environment. To avoid being overstimulated, animals use selective attention. By simply focusing on one thing, humans and other animals can essentially drown out other irrelevant stimuli. This phenomenon requires sensory regulation, especially auditory. To gain insight on how auditory neurons react to both irrelevant and target stimuli, Stony Brook University researcher Pan-tong Yao and his … Continue reading Effects of distractive and target stimuli on auditory neurons within mice brains

Young Investigators ReviewLeave a comment
Cognition

Can video games enhance auditory processing? New research dives deeper into the effects of video gaming on visual and auditory cognitive functions.

Joyce Chen ’23 Within the past few decades, video games have become one of the most universally treasured forms of entertainment among players of all ages. Amongst various genres, action games are widely popularized across the United States. Despite the notable effects that video games have on visual processing, there is a lack of evidence regarding the effect of video games on auditory function. Researcher … Continue reading Can video games enhance auditory processing? New research dives deeper into the effects of video gaming on visual and auditory cognitive functions.

Young Investigators ReviewLeave a comment
Brain

Expectation-induced modulation of metastable activity underlies faster coding of sensory stimuli

Sabah Bari ’24 Expectation is what drives the human brain to perceive our senses. Perception is connected to sensory processing, and the recognition of the stimuli is what determines how accurately and how fast individuals are able to understand it. In the gustatory cortex, the pre-stimulus activity is the anticipation of a specific taste before even consuming a food. The anticipation is a trigger to … Continue reading Expectation-induced modulation of metastable activity underlies faster coding of sensory stimuli

Young Investigators ReviewLeave a comment
Degenerative Disease

Diagnosis and management of Guillain–Barré syndrome in ten steps

Sabah Bari ’24 Guillain-Barré syndrome (GBS) is a rare autoimmune disease characterized by an overactive immune system that causes damage to peripheral nerves, leading to loss of sensorimotor function starting at the extremities and spreading to the torso. Some symptoms of GBS are potentially fatal, such as respiratory failure, cardiac arrhythmias, blood pressure instability, which are all directly involved with the autonomic nervous system. The … Continue reading Diagnosis and management of Guillain–Barré syndrome in ten steps

Young Investigators ReviewLeave a comment