Microdosing Psychedelics

Shahzadi Adeena ’25 In recent years, there has been a growing interest in microdosing psychedelic drugs as a potential tool for enhancing cognitive abilities and improving overall wellbeing. Vince Polito and Richard J. Stevenson of Macquarie University investigated the effects of microdosing psychedelics on psychological variables such as mood, attention, wellbeing, mindfulness, mystical experiences, personality, absorption, creativity, and sense of agency. The researchers hypothesized that … Continue reading Microdosing Psychedelics

Return of Consciousness After Traumatic Brain Injury

Shahzadi Adeena ’25 Understanding the fundamental mechanisms of consciousness, particularly following traumatic brain injury (TBI), is nuanced and challenging. Thalamic function plays a critical role in facilitating consciousness; injury to thalamus-frontal circuitry can impair consciousness. Sima Mofakham and Charles Millek of Stony Brook University hypothesized that thalamocortical projections to the frontoparietal network facilitate the complex dynamics needed for consciousness, and that injury to these connections … Continue reading Return of Consciousness After Traumatic Brain Injury

Racial Disparities in Recommendation of Resective Surgery Undermines Treatment of Brain Tumors

Vignesh Subramanian ’24 Brain tumors—abnormal and typically cancerous growths of uncontrollably multiplying cells—are often first treated using a surgical approach. Benign and malignant brain tumors may be addressed with excision (partial removal) or resection (complete removal) procedures once an evaluation of surgical indications has established their necessity. As such, these procedures require the physicians with whom patients consult—whether neurosurgeons, oncologists, neurologists, or other specialties—to explicitly … Continue reading Racial Disparities in Recommendation of Resective Surgery Undermines Treatment of Brain Tumors

Growth of Artificial Brain Tumors Using Three Dimensional Cell Culture

Julia Chivu ’23 Three dimensional culture systems and patient derived cells successfully allow for tumoroid development. Tumoroids are structures that grow and appear morphologically similar to naturally growing tumors in a patient. Tumoroids show promise for testing new drugs and cancer treatments. For instance, glioblastoma is a form of brain cancer that is aggressive, fast growing, and deadly. In particular, the mesenchymal subtype of this … Continue reading Growth of Artificial Brain Tumors Using Three Dimensional Cell Culture

Racial Disparities in Childhood Adversity Exposure Influence Neuroanatomical Development

Vignesh Subramanian ’24 Childhood adversity is a broad term encompassing a range of experiences and circumstances that negatively impact a child’s well-being and development. Such circumstances include trauma and exposure to violence, all forms of abuse, neglect, exploitation, and family economic hardship, with profound and stratified implications for lifelong health. Lasting effects often include the development of toxic stress responses, accumulating hormones that over-activate certain … Continue reading Racial Disparities in Childhood Adversity Exposure Influence Neuroanatomical Development

Early Taste Experiences Drive Neural Responsiveness and Plasticity in Gustatory Cortex Circuits

Vignesh Subramanian ’24 An individual’s taste preference strongly influences their food choice, impacting their diet and, in turn, their health. Taste preference is defined as an individual’s partiality towards a particular food based on their sensory perception of its taste modalities (sweet, sour, salty, bitter, etc.), flavor, texture, and a host of other factors, and is in part guided by early experiences that identify foods … Continue reading Early Taste Experiences Drive Neural Responsiveness and Plasticity in Gustatory Cortex Circuits

Dancing on the Way to Good Health: The Implications for Culturally Relevant Dancing in the Latino Older Adult Population

Peter Gillespie ’25 Figure 1  Merengue, cha-cha cha, bachata, and salsa are four popular forms of dancing that have the potential to increase physical activity, thereby helping to prevent cognitive decline. Physical activity is crucial in improving the health of older individuals. Within the Latino community, there is a rich cultural history of various genres of dance that may help promote  widespread physical activity among … Continue reading Dancing on the Way to Good Health: The Implications for Culturally Relevant Dancing in the Latino Older Adult Population

Inflammatory diet associated with cognitive impairment 

By: Jessica George, Class of 2024 Figure 1: dietary patterns may predict cognitive decline in older adults Cognitive decline is a major public health concern that affects millions of older adults worldwide. Age-related cognitive decline can lead to mild cognitive impairment, dementia, and other neurodegenerative diseases. While there is no cure for these conditions, early detection and intervention can improve outcomes and quality of life … Continue reading Inflammatory diet associated with cognitive impairment 

Development of Innovative Burn Assessment Technique Using Neural Network

Julia Chivu ’23 The current burn injury evaluation methods available for clinical use are ineffective and outdated. These circumstances are problematic as the initial injury assessment is necessary to ensure the best clinical treatment plan for the patient. Burns can lead to deep tissue damages, necrosis, and severe scarring. Without a proper course of action, the injury can negatively impact the patient’s quality of life, … Continue reading Development of Innovative Burn Assessment Technique Using Neural Network

Non-planned and impulsive suicide attempts associated with low activity of frontal brain 

By: Jessica George, Class of 2024 Figure 1: Global frontal brain activity may be a biomarker for non-planned or impulsive suicide attempts Suicide is a serious public health concern and one of the leading causes of death worldwide. One of the major challenges in preventing suicide is the frequent non-planned or impulsive nature of suicidal behavior, leaving little opportunity for intervention. Therefore, it is essential … Continue reading Non-planned and impulsive suicide attempts associated with low activity of frontal brain 

Intrinsic Biases in Maternal EEG/ERP Research Undermine Racial Representation

Vignesh Subramanian ’24 The use of electroencephalography (EEG) and event-related potentials (ERPs) – two methods of recording brain waves to measure continuous and stimulus-based electrical activity, respectively – is most common in the diagnosis of brain disorders. However, EEG/ERP methodology is also used to monitor the timing of cognitive functions during periods of stress or development. EEG’s high temporal resolution allows for the observation of … Continue reading Intrinsic Biases in Maternal EEG/ERP Research Undermine Racial Representation

EEG Analysis Reveals Association Between Parkinson’s Disease with Visual Hallucinations and Epileptic Discharges

Jessica George ’24 Psychosis in Parkinson’s Disease (PD) is characterized by visual hallucinations (VHs). These VHs have a significant impact on patient’s lives and serve as a reliable predictor for future nursing home institutionalization. Several disorders such as Charles Bonnet syndrome and temporal lobe epilepsy have similar features to those of PD VHs. In the aforementioned disorders, EEG analysis revealed epileptiform discharges, which led researchers … Continue reading EEG Analysis Reveals Association Between Parkinson’s Disease with Visual Hallucinations and Epileptic Discharges