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Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

Vignesh Subramanian, Class of 2024 Figure 1: A thrombectomy is a surgical procedure aimed at removing blood clots lodged in an artery of the brain. A stroke is a medical emergency in which blood flow to the brain is disrupted. Strokes may be ischemic (lacking blood supply to brain tissue due to a blocked artery) or hemorrhagic (involving bleeding into the brain tissue due to … Continue reading Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

Understanding the Neurobiology of Love and Deception

Julia Chivu ’23 Figure 1  Couple holding hands walking towards a multi-colored sunset Recent scientific research has been increasingly focused on better understanding the complex relationship between deception and love. The study of deception within relationships and across genders is essential for interpreting the correlation between human behavior, neural mechanisms, and trust. A research team from Zhejiang Normal University investigated the neurological mechanisms of deception … Continue reading Understanding the Neurobiology of Love and Deception

Racial Disparities in Recommendation of Resective Surgery Undermines Treatment of Brain Tumors

Vignesh Subramanian ’24 Brain tumors—abnormal and typically cancerous growths of uncontrollably multiplying cells—are often first treated using a surgical approach. Benign and malignant brain tumors may be addressed with excision (partial removal) or resection (complete removal) procedures once an evaluation of surgical indications has established their necessity. As such, these procedures require the physicians with whom patients consult—whether neurosurgeons, oncologists, neurologists, or other specialties—to explicitly … Continue reading Racial Disparities in Recommendation of Resective Surgery Undermines Treatment of Brain Tumors

Racial Disparities in Childhood Adversity Exposure Influence Neuroanatomical Development

Vignesh Subramanian ’24 Childhood adversity is a broad term encompassing a range of experiences and circumstances that negatively impact a child’s well-being and development. Such circumstances include trauma and exposure to violence, all forms of abuse, neglect, exploitation, and family economic hardship, with profound and stratified implications for lifelong health. Lasting effects often include the development of toxic stress responses, accumulating hormones that over-activate certain … Continue reading Racial Disparities in Childhood Adversity Exposure Influence Neuroanatomical Development

World Trade Center Responders with Cognitive Impairment Found to Have Decreased Cerebellar Cortical Thickness

Jessica George ’24 There is no doubt that the September 11th attack on the World Trade Center (WTC) left devastating effects on the community. WTC-affected individuals, including survivors, first responders, and those involved in the clean up/recovery operation were exposed to a multitude of physical and psychological stressors. Prior neuroimaging studies demonstrate that WTC responders with cognitive impairment experienced connectivity changes in the white matter … Continue reading World Trade Center Responders with Cognitive Impairment Found to Have Decreased Cerebellar Cortical Thickness

Not A Coincidence: Adolescent Women Are More Likely To Suffer From Depression

Figure 1: Cambridge University research team finds adolescent women’s brain development and genes may make them more likely to suffer from depression. Zhifei Zeng ’23 Women are often perceived to be more prone to being sentimental. This apparent connection may not be coincidental, but rather related to the biological makeup of the female brain. Adolescence is a time of critical brain development, but it is … Continue reading Not A Coincidence: Adolescent Women Are More Likely To Suffer From Depression

Thalamocortical Associated Brain Injuries May be Linked to Behavioral Changes

Sooraj Shah ’24 The discussion of brain injury, particularly in contact sports such as boxing or football, has grown in importance as more and more former athletes speak out on the lingering effects years after retirement. The discovery of CTE (chronic traumatic encephalopathy) in 2002 marked the beginning of increased attention and research into traumatic brain injuries (TBI). While CTE was found to spread throughout … Continue reading Thalamocortical Associated Brain Injuries May be Linked to Behavioral Changes

Brawn Before Brains in Early Mammalian Development

Zhifei Zeng ’23 Of all vertebrates, mammals have the largest brains in terms of absolute size and relative to body size. Significant encephalization (an increase in brain size relative to body size) has been observed in the placenta of extant mammals. However, until recently it has not yet been determined when mammalian brains began to increase in size and how they evolved to their current … Continue reading Brawn Before Brains in Early Mammalian Development

The Effect of Electrotherapy on Brains Addicted to Video Games

Ishmam Khan ’25 Although video games may represent a sanctuary from the stresses of daily living, young people, especially teens, are susceptible to becoming addicted to gaming platforms. According to the Diagnostic and Statistical Manual of Mental Disorders, Internet Gaming Disorder (IGD) results in an irresistible compulsion to play video games, which may lead to declining mental health and daily function. Currently, one common technique … Continue reading The Effect of Electrotherapy on Brains Addicted to Video Games

Electrical Impulses May Be The Best Way to Treat Mental Illnesses

Aditi Kaveti ’23 Mental illnesses span a wide range of health conditions, including disorders that affect one’s mood, thinking, and behavior. Some severe cases of these conditions may be medication-resistant. For example, some patients with epilepsy are known to have significant anxiety associated with the condition that cannot be treated with medication. A study recently published in Nature Biomedical Engineering addresses medication-resistant disorders by studying … Continue reading Electrical Impulses May Be The Best Way to Treat Mental Illnesses

Loss of Dopamine Impairs Voluntary Movement in Parkinson’s Disease

Sooraj Shah ’24 For years, the correlation between loss of the hormone dopamine and the development of Parkinson’s Disease (PD) has been evident. Dopamine is a neurotransmitter that assists in the propagation of electrical signals in the brain, which facilitate everyday movements such as walking and writing. A reduction of dopamine levels in an individual with Parkinson’s disease may lead to shaking and poor coordination. … Continue reading Loss of Dopamine Impairs Voluntary Movement in Parkinson’s Disease

Breeding Alters Dog Brains

Sabah Bari ’24 Over centuries, dogs have been bred to be domesticated and to be specialized in specific jobs. Stony Brook researchers have discovered that the dog’s brain structure is being altered through breeding, which allows the dogs to perform specific tasks. Selective breeding is the term used to describe how humans choose the parents of the dogs to create offspring with desirable traits. These … Continue reading Breeding Alters Dog Brains