Depression May Be Linked To Specific Lipid Ratios Within The Body

Joyce Chen ’23 Depression is a chronic disease that affects quality of life by reducing one’s interest in basic activities and hobbies due to continual feelings of sadness and low self-esteem. Previous studies have proposed that low high-density lipoprotein cholesterol (HDL-C) levels play a key role in depression because of changes in serotonin and lipid metabolism. There is little research on how depression is affected … Continue reading Depression May Be Linked To Specific Lipid Ratios Within The Body

Loss of NG2 Glia Implicated in Emergence of Depression Symptoms

Vignesh Subramanian ’24 Glia are non-neuronal cells that host and provide a number of homeostatic ancillary functions in both the central (CNS) and peripheral (PNS) nervous systems. Though only recently discovered and characterized, glial cells vastly outnumber neurons and provide them with structural support and insular protection, driving their myelination (the process of forming coverings known as myelin sheaths that coat neurons’ signaling axons), facilitating … Continue reading Loss of NG2 Glia Implicated in Emergence of Depression Symptoms

The Effect of Coffee and Caffeine on Healthcare Workers in Iran

Yukta Kulkarni ’22 Coffee, specifically the consumption of caffeine, is prevalent across the world. When studying the effects of caffeine on psychological disorders, previous studies have led to inconclusive results. However, most of the research has been completed in Western and first-world countries. Since there are differences in culture and nutrition in varying regions, it is important to see the effects of caffeine in other … Continue reading The Effect of Coffee and Caffeine on Healthcare Workers in Iran

Square Dancing can Improve Cognitive Performance in Older Women

Yukta Kulkarni ’22 It is a well-known fact that exercise has many physical and psychological benefits. For example, persistent exercise is associated with increased muscle strength, a better metabolism, and even improving mood. Amidst common forms of exercise such as weight lifting and running, other activities such as dancing can fall into this category. Previous studies have shown that dancing offers advantages such as improvements … Continue reading Square Dancing can Improve Cognitive Performance in Older Women

History of Maternal Depression May Correlate with Hippocampal Volume in their Children

Yukta Kulkarni ’22 Depression is defined as a mental disorder in which a person has consistent feelings of sadness and a severe loss of interest. Affecting all age groups, parents can be inflicted with depression or depression-like symptoms. Previous studies have found that children of parents suffering from depression have an increased risk of developing psychiatric disorders during their lifetimes. However, the process of how … Continue reading History of Maternal Depression May Correlate with Hippocampal Volume in their Children

Money Matters: Investigating Neural Responses to Monetary and Social Feedback

Thumyat Noe ’23 Depression and social anxiety disorders are two of the most common psychopathologies in adults. One way to identify these disorders is by looking at event-related potentials (ERPs) which are measurable brain responses to stimuli. “Reward positivity” is an event-related potential that reflects neural positivity toward rewards and activation of a reinforcement learning system. Previous studies suggest that smaller reward positivity potentials correlate … Continue reading Money Matters: Investigating Neural Responses to Monetary and Social Feedback

Grip Strength as an Avenue of Depression Prediction

Sooraj Shah ’24 Depression is a mental state in which individuals often feel disinterested in everyday activities, preventing them from taking advantage of life’s opportunities. Interestingly, depression seems to take a physical form as well, with muscle strength and functionality being a main area of concern. Unfortunately, muscle failures often go untreated because the majority of people with depression tend to reject treatment. In a … Continue reading Grip Strength as an Avenue of Depression Prediction

The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

Alex Moir ’23 Human herpesvirus 6B (HHV-6B) is one of the most prevalent herpesviruses amongst tested populations, with estimates placing worldwide infections near 100%. HHV-6B is neurotropic, establishing a lifelong infection in the brain and entering a period of latency in which replication and spread is inhibited. The activity of HHV-6B and its effects on the brain during latent infection are poorly understood. Examination of … Continue reading The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

The COVID-19 Pandemic: A Physical and Mental Crisis

Wendy Wu ’22 In March 2020, the World Health Organization declared the COVID-19 crisis a global health pandemic. Days later, COVID-19 was declared a national emergency in the U.S. Cases rose alarmingly and multiple states went into shut-down. Schools and workplaces closed, moving to online platforms as an effort to socially distance and slow the spread of the virus. What was thought to be a … Continue reading The COVID-19 Pandemic: A Physical and Mental Crisis

The Effects of Mental Health of Young Children on their Adolescent Functioning

Yukta Kulkarni ’22 Psychopathology is the study of mental disorders, which can be prevalent in all age groups. In fact, children can be tested and diagnosed as early as preschool. It has been observed that young children who show symptoms of disorders  may endure the same symptoms at an exacerbated level in later childhood or even adolescence. However, little is known about how these disorders … Continue reading The Effects of Mental Health of Young Children on their Adolescent Functioning

Does Reward Responsivity Moderate or Mediate Effects of Parental Depression on Offspring?

Panayiota Siskos 2023 Figure 1: Depression alters the reward responsivity, and is described as having less tendency to adjust behavior or put in effort for rewards. Depression has alterations in reward responsiveness constructs with subjective experiences of pleasure and neural activation for rewarding. Alterations may be assessed with neurophysiological measures including reward positivity event-related potential which correlates with positive emotionality in kids, behavioral, and self-report … Continue reading Does Reward Responsivity Moderate or Mediate Effects of Parental Depression on Offspring?

Depressive symptoms can lead to a false perception of ambiguity

Joyce Chen ‘23 Unlikely to experience optimism, many depressed individuals often times perceive ambiguity in a negative fashion. Their perception of reality is morphed by their emotions and they misunderstand other people’s intentions due to their subjective feelings. They have a negatively biased interpretation of the world, thereby leading to self-doubt and isolation. Thus, a depressed disposition can cause and worsen negative ambiguity processing.  A … Continue reading Depressive symptoms can lead to a false perception of ambiguity