Julia Chivu ’23 Figure 1  DNA strand unwinding causing the formation of the replication fork followed by DNA replication. Genomic DNA is constantly at risk of molecular decay. To address this issue, base excision DNA repair (BER) plays a critical role in fixing the minor DNA damage. In particular, Ape1 (or apurinic/apyrimidinic endonuclease) is a multifunctional protein that is a key component in BER. Ape1 … Continue reading Investigating the Unexpected Results of Ape1 Inhibitors