Category: Year

2017-18

EYA1 and its Overexpression in Colorectal Cancer Associated with Angiogenesis

By Daniel Walocha ‘19 Angiogenesis is the formation of blood vessels. Cancer cells release growth factors associated with the induction of angiogenesis. Newly formed blood vessels allow cancer cells to easily metastasize, making treatment and survivability difficult for tumors. Colorectal cells are the third leading cause of cancer deaths, so understanding potential therapeutic targets is of interest to researchers. Shaoxin Cai, Ph.D, from Tongji Hospital … Continue reading EYA1 and its Overexpression in Colorectal Cancer Associated with Angiogenesis

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2017-18, Interview

Student Researcher Interview with Dhaval Shah

Interviewer: Benjamin Kerner Interviewed: Dhaval Shah B: Alright so first question, what is your name, major and what department of research do you work out of? D: Dhaval Shah, and Psychology with a Biology minor, and I work in the Periodontal department at the dental school of… It’s like a long name for the lab, but I won’t go into that.  Essentially a regeneration lab. … Continue reading Student Researcher Interview with Dhaval Shah

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2017-18

Arsenic and Copper May Affect Reproductive Health in Chickens

By Matthew Lee ‘21 Arsenic and copper are trace elements that can have deleterious health effects when present in the body in large quantities. Their toxicity in certain body parts such as the liver, nervous system, and lungs is well documented. However, the effects of arsenic and copper on testicular tissues are not as studied. A recent study led by Yizhi Shao of Northeast Forestry … Continue reading Arsenic and Copper May Affect Reproductive Health in Chickens

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2017-18

TRIM25 and its Role in the Proliferation of Colorectal Cancer Cells

By Daniel Walocha ‘19 Colorectal cancer (CRC) is the third leading cause of cancer death. Metastasis is one of the largest determinants of survival for colorectal cancer; treatment before metastasis is crucial for survival. Targeting potential gene products that promote proliferation and invasion could reduce cancer metastasis and growth. TRIM25 is an E3 ubiquitin ligase found to be responsible for the polyubiquitination of retinoic acid … Continue reading TRIM25 and its Role in the Proliferation of Colorectal Cancer Cells

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2017-18

Reactive Oxidative Species Sensitivity in Cancer

By Daniel Walocha ‘19 Cancer cells primarily use glycolysis to gain ATP and important intermediates for amino acid biosynthesis via the Warburg effect, even in the presence of readily available oxygen. This highlights a key distinction between cancer and normal cells: normal cells mainly utilize the electron transport chain for their ATP needs, while cancer cells do not. As a result, cancer cells build up … Continue reading Reactive Oxidative Species Sensitivity in Cancer

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2017-18

Energy, Spin, and Charge All in One

Neomi Lewis ‘21 The field of economics is constantly making strides to better manipulate and strategically implement properties of charged particles. Charged particles play instrumental roles in devising electronic devices. Most particles that are commonly used, however, only retain one property that can be manipulated. Researchers from Duke University now have reason to believe that “trions,” a quasiparticle, can also be controlled in useful ways. … Continue reading Energy, Spin, and Charge All in One

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2017-18

Exploring Saccadic Eye Movement

By Fatin Chowdhury ‘19 The nuances of eye movements form an overlooked part of human vision. Dr. Grace Edwards at Istituto Italiano di Technologia in Italy examined the effect of peripheral information near a saccade target. Saccading is the completion of rapid eye movement by healthy human eyes while being fixated on differing spatial points. Edwards hypothesized that the neural interpretation of a postsaccadic visual … Continue reading Exploring Saccadic Eye Movement

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2017-18

The Largest Map of the Milky Way Yet

Neomi Lewis ‘21 The glaring image of the Milky Way is the rotating galaxy that usually comes to mind when individuals think about outer space. However, this typical image is no longer useful in studying bodies within the galaxy. Images of the Milky Way captured in visible light are obscured by dust and clouds. To remedy the situation, astronomers have used a 45 m radio … Continue reading The Largest Map of the Milky Way Yet

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2017-18

Effects of Clock-Shifting Wild Seabirds

By Fatin Chowdhury ‘19 Humans have been curious about animal navigation for millennia, but the strategies and adaptations used by non-human organisms to travel are still unknown. Oliver Padget, a doctoral student at Oxford University in England, recently published findings that examined the impact of solar orientation on pelagic seabird navigation patterns. The study suggested that by using the sun as a compass, animals can … Continue reading Effects of Clock-Shifting Wild Seabirds

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2017-18

Using Stars to Find Dark Matter

Neomi Lewis ‘21 Astronomers and cosmologists continue the elusive search to understand the nature and existence of dark matter, a substance that is believed to be pervasive throughout the universe, including near our own planet. An international group of astrophysicists have published work in the journal Physical Review Letters this January that suggests that we may be able to better decipher the speed of dark … Continue reading Using Stars to Find Dark Matter

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2017-18

Diagnosing Necrotizing Soft Tissue Infections via CT Scans

By Fatin Chowdhury ‘19 Imaging technology has become more useful for preventing surgery and aiding in its success. Technologies such as CT (computed tomography) scans have expanded the breadth of diagnostic methodologies available to physicians. Dr. Myriam Martinez in Boston, Massachusetts, sought to pinpoint the usefulness of CT technology in allowing for necrotizing soft infections (NSTI) diagnoses. The researchers found that NSTIs could be examined … Continue reading Diagnosing Necrotizing Soft Tissue Infections via CT Scans

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2017-18

Genomic Analysis of Antibiotic Resistant Bacteria

Gene Yang ‘19 Methicillin-resistant Staphylococcus aureus, also known as MRSA, is an antibiotic-resistant bacteria that infects approximately 90,000 people in the United States each year. This bacteria’s resistance to many common drugs, including penicillin, makes it a rising public health care threat, yet our understanding of MRSA at the genetic level is limited. In order to bridge this gap, scientists at the University of San … Continue reading Genomic Analysis of Antibiotic Resistant Bacteria

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