Inhibition of Sterylglucosidase May Lead to Improved Class of Antifungal Agents

Robyn Rutgers ’24 Upon entering the lungs, the fungal pathogen Cryptococcus neoformans (CN) disseminates through the bloodstream and can cause life-threatening meningitis in immunocompromised patients. Currently, there are a number of major drawbacks in current antifungal agents such as high toxicity, limited availability, and a narrow spectrum of activity. Therefore, the development of new pharmacological agents is critical in combating fungal pathogens such as CN. … Continue reading Inhibition of Sterylglucosidase May Lead to Improved Class of Antifungal Agents