By Adil Ali Khan, Class of 2029 Figure 1: A Niemann Pick cell in the spleen Acid sphingomyelinase (aSMase) is an enzyme that hydrolyzes sphingomyelin (SM) to ceramide and phosphocholine. Niemann-Pick Disease (NPD) is a lysosomal storage disorder caused by impairment or loss of aSMase. It presents in two forms: Type A, which is severe, and Type B, which is milder. The gene that codes … Continue reading Protecting the Brain: How a CRISPR Mutation Safeguards Neurons