Activating the Enzyme of Youth

Ashley Goland ’23 The cause of aging has long been one of mankind’s favorite mysteries to entertain, and as science advances, its secrets are gradually being stripped away. Studying chromosome structure revealed sections called telomeres, sequences of repeated nucleotides on the ends of a chromosome that serve to prevent its deterioration, and from this discovery came a revelation about age. Aging-related diseases such as dementia, … Continue reading Activating the Enzyme of Youth

New Findings in Telomerase Activity and the Potential for Immortality

By Marcia-Ruth Ndege ‘21 The telomerase enzyme catalytic cycle limits the telomerase enzymes’ ability to synthesize specific DNA segments of six nucleotides called repeats. These repeats, known as telomeres, are protective caps that prevent the destabilization of the genome by lengthening the ends of chromosomes. However, these protective caps shorten every time a cell divides. A cell’s telomere length, therefore, determines when a cell will … Continue reading New Findings in Telomerase Activity and the Potential for Immortality