Vignesh Subramanian ’24 Huntington’s disease (HD) is a genetic neurodegenerative disorder that causes progressive development of involuntary movements and decline of memory and cognitive abilities. The disease is characterized by the aggregation of abnormally long huntingtin protein (mHtt), a product of mutations in the HTT gene that cause excessive ‘CAG’ nucleotide sequence repeats within the protein’s coding DNA sequence. Such mHtt aggregation triggers cell death … Continue reading Effects of Huntington’s Disease Pathology Observable in Retinal Function