Cholinergic Interneurons and Nicotinic Receptors are drivers of Serotonin Release in the Dorsal Striatum
By Kang Lai 2026 The dorsal striatum is a major input region of the basal ganglia and plays critical roles in goal-directed and habit learning. Neural processes within this region are largely shaped by serotonin, also known as 5-HT. Previous research has shown that monoamines and acetylcholine (ACh) can regulate the release of each other in the striatum. For example, dopamine causes excitation of striatal … Continue reading Cholinergic Interneurons and Nicotinic Receptors are drivers of Serotonin Release in the Dorsal Striatum

