Figure 1: The poison frog, Ameerega bassleri, is one of the three studied lineages of frogs that evolved resistance to epibatidine, a toxin lethal in microgram-doses.

Poison Frogs: Evolution of Epibatidine Resistance

Gene Yang ‘19 Animals that use toxins as anti-predator defense usually evolve a method of resistance, often at a high physiological cost, to prevent self-intoxication. Poisonous frogs, a broad polyphyletic group within the order Anura, often use one such method known as target site insensitivity, which is the alteration of the molecular target of the toxin to disallow the toxin from binding. Researchers from University … Continue reading Poison Frogs: Evolution of Epibatidine Resistance