The Use of CRISPR/Cas9 Gene Editing Tool in Treating Early Onset Alzheimer’s Disease

Stephanie Budhan ‘20 Early-onset Alzheimer’s disease (AD) is dominantly inherited genetic disorder that causes the development of Alzheimer’s Disease in individuals younger than 65 years old. AD is caused by a point mutation in three major genes, one of which is amyloid precursor protein (APP). APP is cleaved to generate beta amyloid which makes up the amyloid plaque found in the brains of AD patients. … Continue reading The Use of CRISPR/Cas9 Gene Editing Tool in Treating Early Onset Alzheimer’s Disease