Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

Vignesh Subramanian, Class of 2024 Figure 1: A thrombectomy is a surgical procedure aimed at removing blood clots lodged in an artery of the brain. A stroke is a medical emergency in which blood flow to the brain is disrupted. Strokes may be ischemic (lacking blood supply to brain tissue due to a blocked artery) or hemorrhagic (involving bleeding into the brain tissue due to … Continue reading Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

Nerinetide Application Establishes Reperfusion in Ischemic Stroke Patients Receiving Non-Standard Post-EVT Care

Vignesh Subramanian ’24 Ischemic stroke, the subtype accounting for the vast majority of strokes, frequently occurs following obstruction of blood vessels by plaques or clots. This cerebrovascular accident is often characterized by the debilitating effects of postsynaptic density protein 95 (PSD-95), a scaffolding protein that typically mediates localization of neurotransmitter receptors such as NMDARs but does so excessively in the wake of strokes, triggering mass … Continue reading Nerinetide Application Establishes Reperfusion in Ischemic Stroke Patients Receiving Non-Standard Post-EVT Care