The Effects of the Gut on Fruit Flies’ Lifespans

By Caleb Sooknanan ‘20 Aging and chronic diseases are often associated with effects such as metabolic and oxidative stresses, inflammation, and mitochondrial deficiencies. Scientists have suggested that changes in organisms’ gut microbiota relate to specific gut phenotypes, while probiotics can be ingested to regulate chronic disease progression in conjunction with microbiota changes. However, more research is needed to understand how gut microbiota could be attributed … Continue reading The Effects of the Gut on Fruit Flies’ Lifespans

Figure 1. Scientists from UCLA controlled expression of genes Drp1 and Atg1 in fruit flies to promote breakdown and removal of damaged mitochondria.

Controlling Mitochondria to Stop the Clocks

By Meghan Bialt-DeCelie ’19 The respiratory function of the mitochondrion, the energy producing organelle found in the cell, can decline over time. This is because of how the mitochondrion enlarge and assume a more elongated shape. Typically, that mitochondrion will eventually break down and get removed processes called mitochondrial fission and mitophagy respectively. Accumulation of the ineffective mitochondria and inability to remove them are major … Continue reading Controlling Mitochondria to Stop the Clocks