Do Signals in the Brain Control Our Taste Preferences?

Kang Lai, Class of 2026 Our perception of taste profoundly influences our calorie intake and food preferences, and even serves as a defense mechanism from harmful substances. The gustatory insular cortex, a key brain region associated with taste, is closely linked to eating patterns and disorders. While neuronal circuits in this region have been studied, its neurochemical signaling remains obscure.  The Maffei lab at Stony … Continue reading Do Signals in the Brain Control Our Taste Preferences?

Presynaptic Inhibition of GABAA Receptors Possible in Thalamocortical Circuits

Vignesh Subramanian ’24 A number of neurodegenerative disease processes, including those of temporal lobe epilepsy, GABA-transaminase deficiency, and traumatic brain injury, involve disruptions to the signalling pathway of gamma-aminobutyric acid (GABA), the chief inhibitory neurotransmitter of the central nervous system. Conventional understanding divides the ability of GABA to block neural signaling into ‘presynaptic inhibition’ – involving suppression of glutamate release,  an excitatory counterpart neurotransmitter – … Continue reading Presynaptic Inhibition of GABAA Receptors Possible in Thalamocortical Circuits