
The Use of Focused Ultrasound for Enhanced Delivery of Gene Therapy Across the Blood-Brain-Barrier
Jorge Pincay ‘20 Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease that results in the degradation of nerve cells in the brain over time. This disease is the result of a DNA mutation — a cytosine-adenine-guanine (CAG) trinucleotide repeat expansion– that occurs in the gene that encodes for the huntingtin (Htt) protein. This repeat expansion causes a highly toxic form of the Htt protein … Continue reading The Use of Focused Ultrasound for Enhanced Delivery of Gene Therapy Across the Blood-Brain-Barrier