Melittin: A Natural Peptide from Bee Venom Which Induces Apoptosis in Human Leukemia Cells

Thumyat Noe ’23 Past research has shown that honeybee’s venom has the potential to treat various diseases such as arthritis, chronic pain, cancer, and atopic dermatitis. The venom mostly consists of peptides and low molecular weight compounds such as sugars and amino acids. Melittin is one of the peptides found within honeybee’s venom and possesses the most bioactive properties among all the compounds in the … Continue reading Melittin: A Natural Peptide from Bee Venom Which Induces Apoptosis in Human Leukemia Cells

Inducing Leukemia Cell Death Through the Inhibition of Amino Acids

By Riya Gandhi ‘22 Thanks to chemotherapy, acute myeloid leukemia (AML) is not the most fatal kind of cancer. However, the same chemotherapy that treats the disease may also revitalize leukemia stem cell populations, thereby increasing the probability of relapse. As such, scientists are still actively researching alternative treatments and cures. Most recently, researchers looked into the importance of amino acids for preventing the growth … Continue reading Inducing Leukemia Cell Death Through the Inhibition of Amino Acids

Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse

By Riya Gandhi ‘22 Relapse of acute myeloid leukemia (AML) — or any type of cancer, for that matter — has always posed an enormous challenge to patients and physicians alike. However, a recent study conducted by researchers at McMaster University has found that it is not predominantly leukemic stem cells that induce such recurrence but rather leukemic-regenerating cells that arise post-chemotherapy. In this study, … Continue reading Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse