The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

Alex Moir ’23 Human herpesvirus 6B (HHV-6B) is one of the most prevalent herpesviruses amongst tested populations, with estimates placing worldwide infections near 100%. HHV-6B is neurotropic, establishing a lifelong infection in the brain and entering a period of latency in which replication and spread is inhibited. The activity of HHV-6B and its effects on the brain during latent infection are poorly understood. Examination of … Continue reading The Potential Biological Role of Latent-Phase Herpesvirus on Mental Health

Mucopolysaccharidoses Treatment with Gene Therapy

By Daniel Walocha ‘19 Muscopolysaccharidoses (MPS) is a lysosomal storage disorder which results from a deficiency of lysosomal enzymes. The lack of enzymes causes an accumulation of glycosaminoglycans that can lead to severe symptoms including heart disease, nervous system damage, and skeletal dysplasia. Enzyme replacement therapies, hematopoietic stem cell transplantation, and substrate reduction therapy are short-lived and temporary resolutions that cannot reach a number of … Continue reading Mucopolysaccharidoses Treatment with Gene Therapy