Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

Author: Vignesh Subramanian, Class of 2024 Figure 1: Increasing evidence suggests biological aging, measured by examining the extent of methylation of cells’ DNA, is a stronger predictor of diminishing cognitive abilities than chronological age.  Title: Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age Age acceleration is the term used to describe the difference between an individual’s chronological age, the length of time … Continue reading Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

The Influence of Epigenetic Age on Cognitive Decline

 Julia Chivu ’23 As people age, their cognitive abilities tend to decline. While chronological age is commonly cited as a reason for this decline, it often fails to explain why some individuals have higher cognitive performance than others of the same age. To address this, epigenetic clocks, which analyze DNA methylation at specific genomic sites correlated with aging, are emerging as useful tools for predicting … Continue reading The Influence of Epigenetic Age on Cognitive Decline

FGF21 Is Associated with Cognitive Impairments in Non-Elderly Patients

By Maryna Mullerman ’20   Patients with metabolic syndrome (MetS), associated with cognitive decline, often express elevated levels of fibroblast growth factor 21 (FGF21), an endocrine hormone for metabolic regulation. Arintaya Phrommintikul and researchers from Chiang Mai University in Thailand investigated the link between FGF21 and cognitive decline in elderly and non-elderly patients. They hypothesized that FGF21 levels corresponded with cognitive performance in younger and … Continue reading FGF21 Is Associated with Cognitive Impairments in Non-Elderly Patients

Figure 1. Older students were more successful at university curriculum than their younger peers.

Age Is No Barrier For Academic Success

By Maryna Mullerman ’20 Many studies have explored academic success predictors in young adults. In recent years, however, more people over the age of 60 have undertaken university educations. Abbie-Rose Imlach and researchers from the University of Tasmania in Australia hoped to identify cognitive, psychological, social, and genetic factors that influenced academic performance in older adults. The researchers hypothesized that factors such as genetic polymorphism, … Continue reading Age Is No Barrier For Academic Success