Live Imaging of Cell Cycle State in Metazoa

Gaurav Sharma ’22 An important part of development of any organism is differential regulation of the cell cycle since it leads to cell specification and differentiation. The cell cycle states and their coordination are already well-studied, but the mechanistic connection between the cell cycle and differentiated cell behavior is still to be determined. The challenge is finding a reliable live cell imaging tool that can … Continue reading Live Imaging of Cell Cycle State in Metazoa

Nanoparticles May Be the New Future for Cancer Immunotherapy

Gaurav Sharma ’22 Cancer immunotherapy has been extensively explored and requires information of the tumor’s antigen presentation in order for a method to be selected. An approach that is more effective and has a broader range had not been found that did not have the constraint of needing the information of the tumor’s antigen presentation. Researchers at Johns Hopkins School of Medicine and Johns Hopkins … Continue reading Nanoparticles May Be the New Future for Cancer Immunotherapy

Anchor-Cell Invasion Regulation Network Discovered

Gaurav Sharma ’22 Invasion through the basement membrane is essential to many cellular and biological processes such as embryonic development, immune response, tissue development, and metastasis. The components and mechanism of basement membrane invasion is known. There are four transcription factors that regulate anchor-cell invasion; fos-1, hlh-2, nhr-67, and egl-43. The Matus Lab at Stony Brook University sought to answer the question of how all … Continue reading Anchor-Cell Invasion Regulation Network Discovered

Inactivated Gene Linked to Kidney Cancer and Tumor Development in Mice

Gaurav Sharma ’22 The epigenetic components pertaining to the onset of cancer have been of interest for many years due to the hope of developing approaches to delay the onset of cancer in the future for an individual. Recently, a tumor suppressor family has been discovered, called Ras-Association Domain Family (RASSF) which epigenetically inactivated breast, lung, skin, and thyroid cancers. Neither RASSF10’s in-vivo function nor … Continue reading Inactivated Gene Linked to Kidney Cancer and Tumor Development in Mice