Figure 1. Reduced insulin signaling maintains “youthful” response in aging flies and can potentially prevent age-related neuronal decline.

Reduced Insulin Levels Can Prolong Neuron Longevity

By Maryna Mullerman ’20 Reduced insulin-like signaling (IIS) can lead to diabetes and damage of neuronal function in metabolism. However, chronically lowered insulin/insulin-like growth factor (IGF) may improve neurodegenerative disease defects. Hrvoje Augustin and researchers at University College London analyzed the escape response mechanism of the fly Drosophila melanogaster and the effects of genetically weakened insulin signaling on this model. This was done to explore … Continue reading Reduced Insulin Levels Can Prolong Neuron Longevity