Tag: Neurogenesis

2024-25, Biology, Degenerative Disease, General Neuroscience, Neuroscience

Neurogenesis and Repair Mechanisms Following Traumatic Brain Injury: Insights from Mouse Models

Kang Lai, Class of 2026 Traumatic Brain Injury (TBI) is one of the most common causes of cognitive defects affecting both physical and mental functions of the brain. Its implications span from cognitive defects to motor dysfunction to behavioral disorders–all of which permanently and severely diminish quality of life. TBI also greatly disrupts neurogenesis–the formation of new neurons– and neuronal stem cell regeneration. At the … Continue reading Neurogenesis and Repair Mechanisms Following Traumatic Brain Injury: Insights from Mouse Models

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Molecular Biology

NSC-Derived Antibody Proves a Selective NSC Marker

Vignesh Subramanian ’24 Neural stem cells (NSCs) are multipotent cells capable of differentiating into the major types of mature cells in the central nervous system (CNS) – neurons and glia – and giving rise to unlimited generations of those cells. Alongside progenitor cells, which are descended from NSCs and differentiate into specific target cells, NSCs are critical in advancing neurogenesis, the development of neurons from … Continue reading NSC-Derived Antibody Proves a Selective NSC Marker

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Brain

Neurogenesis and its Implications on Brain Development

By Snigdha Kanadibhotla ‘21 Conventionally, humans were thought to be born with a fixed number of nerve cells or neurons that steadily deteriorated over their lifetime; as a result, degenerative brain diseases were thought to be untreatable. However, studies involving animal models have challenged this idea by demonstrating that during adulthood, neurogenesis or the creation of new neurons can occur in the hippocampus which isa … Continue reading Neurogenesis and its Implications on Brain Development

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