Flavonoids to the Rescue: Combating Age-Related Neurodegeneration

Sean Krivitsky, Class of 2026 Neurodegeneration, which is often associated with aging, leads to the development of serious diseases, including Alzheimer’s disease and Parkinson’s disease, that afflict more than 50 million people worldwide. In addition to their devastating impact, neurodegenerative diseases are particularly problematic regarding their prognosis, diagnosis, and treatment. One of the primary factors underlying the development of neurodegenerative diseases is mitochondrial dysfunction. This … Continue reading Flavonoids to the Rescue: Combating Age-Related Neurodegeneration

Nerinetide Application Establishes Reperfusion in Ischemic Stroke Patients Receiving Non-Standard Post-EVT Care

Vignesh Subramanian ’24 Ischemic stroke, the subtype accounting for the vast majority of strokes, frequently occurs following obstruction of blood vessels by plaques or clots. This cerebrovascular accident is often characterized by the debilitating effects of postsynaptic density protein 95 (PSD-95), a scaffolding protein that typically mediates localization of neurotransmitter receptors such as NMDARs but does so excessively in the wake of strokes, triggering mass … Continue reading Nerinetide Application Establishes Reperfusion in Ischemic Stroke Patients Receiving Non-Standard Post-EVT Care