Breast Cancer Insights and Potential Treatments

Sean Krivitsky ‘27 Figure 1. HER2 is a protein that has been strongly implicated in many human cancers, particularly breast cancer, and has been demonstrated to induce carcinogenesis through a variety of different mechanisms. This breast cancer tissue has been stained for HER2. Some of the latest research by Stephen J. Collins of the Miller lab, a part of Stony Brook University’s Department of Physiology … Continue reading Breast Cancer Insights and Potential Treatments

Urea-Resistability of Shark Myosin: Insights into Protein Stability and Potential Therapeutic Implications

Justin Lim ’26 Figure 1: White shark.jpg Urea, a common byproduct of protein metabolism, is excreted through urine in most urea-producing organisms due to its toxic properties in high concentrations. Specifically, urea’s nitrogen content can destabilize the structure of proteins by weakening their folded structure. Sharks have chemical countermeasures to halt the progression of protein denaturation through the use of trymethylamine N-Oxide (TMAO), a molecule … Continue reading Urea-Resistability of Shark Myosin: Insights into Protein Stability and Potential Therapeutic Implications