How Does the Brain Learn Taste Aversion?

Ayesha Azeem ‘23 The gustatory system is the sensory system that allows humans to perceive the sense of taste, or flavor. Humans are able to perceive different flavors via the taste receptors on taste buds, which can be found on the upper surface of the tongue as well as on the epiglottis. Taste perception depends on the chemical characteristics of the stimulus, as well as … Continue reading How Does the Brain Learn Taste Aversion?

D-Serine Infusion Mitigates Neuronal Losses Preceding Temporal Lobe Epileptic Attacks

Vignesh Subramanian ’24 Temporal lobe epilepsy (TLE) is the most common form of both focal epilepsy – the recurrence of seizures in one hemisphere of the brain – and drug resistant epilepsy. The disease is characterized by neuronal cell death in Layer 3 (L3) of the medial entorhinal area (MEA), the internal region of the temporal lobe constituting memory and higher-order cognitive functioning. Recent studies … Continue reading D-Serine Infusion Mitigates Neuronal Losses Preceding Temporal Lobe Epileptic Attacks

Presynaptic Inhibition of GABAA Receptors Possible in Thalamocortical Circuits

Vignesh Subramanian ’24 A number of neurodegenerative disease processes, including those of temporal lobe epilepsy, GABA-transaminase deficiency, and traumatic brain injury, involve disruptions to the signalling pathway of gamma-aminobutyric acid (GABA), the chief inhibitory neurotransmitter of the central nervous system. Conventional understanding divides the ability of GABA to block neural signaling into ‘presynaptic inhibition’ – involving suppression of glutamate release,  an excitatory counterpart neurotransmitter – … Continue reading Presynaptic Inhibition of GABAA Receptors Possible in Thalamocortical Circuits

Priming of long-term memory from initial experience alters future learning

Joyce Chen ’23 One of the most fascinating things about the brain is its malleability. When humans learn, whether it be in the classroom or from an experience, the brain produces new neurons so that the information can be recalled in the future. This is a process known as neuronal plasticity. Although there is plenty of research surrounding this area, there is still much more … Continue reading Priming of long-term memory from initial experience alters future learning

Ethnic Diversity and Recall: Is there a connection?

Yukta Kulkarni ’22 People spend thirteen years of their lives, from around five to eighteen years old, in school, where they learn both academic content and social etiquette. They may then go on to university and reinforce these skills and knowledge. Thus, students require not only a good memory, but also the ability to collaborate with others. However, not all students benefit equally from working … Continue reading Ethnic Diversity and Recall: Is there a connection?

Differences of Cognitive Offloading Usage among Individuals Performing Short Term Memory Tasks

Sooraj Shah ’24 Recalling a lot of information at one time is possible, but not feasible. Writing information down on a paper during a class or in the grocery store, for instance, are ways to reduce the strain of memorization within an individual. This concept is further defined as cognitive offloading, which can assist in overcoming the cognitive restraints in mentally retaining information. A study … Continue reading Differences of Cognitive Offloading Usage among Individuals Performing Short Term Memory Tasks

Neural Population Code Organization in Mouse Visual System

Panayiota Siskos ’23 While mice are useful for investigating components of visual perception, this research is limited by insufficient knowledge of the organization of the visual cortex of the mice. Visual information is processed via computations while traveling from the retina to lateral geniculated nucleus and visual cortices. The early visual system processes complex visual stimuli by encoding various stimulus attributes by individual neurons while … Continue reading Neural Population Code Organization in Mouse Visual System

Presence of Seizure-Inducing Lesions Observable with Brain Tonometry

Vignesh Subramanian ’24 Cortical dysplasia (CD) is a congenital disorder involving improper organization of layers of the brain, which generates pathological lesions on the organ’s surface and renders developing neurons unable to mature and connect with one another. Lesional tissue significantly increases risk of refractory epilepsy (seizures not responsive to medication) in the pediatric population, and complete surgical resection of this deformed tissue is a … Continue reading Presence of Seizure-Inducing Lesions Observable with Brain Tonometry

Anatomical Etiology of AR Subtype of Parkinson’s Disease Linked to Altered Functional Connectivity

Vignesh Subramanian ’24 Parkinson’s disease (PD) is a neurodegenerative movement disorder causing progressive loss of motor control that afflicts over ten million people worldwide. The disease is characterized by a loss of dopaminergic neurons in the substantia nigra region of the brain, contributing to widespread network alterations that disrupt communication with the body’s muscles. PD patients are classified by their most prominent resulting clinical symptoms, … Continue reading Anatomical Etiology of AR Subtype of Parkinson’s Disease Linked to Altered Functional Connectivity

Deaf People and Sensory Compensation

Ayesha Azeem ‘23 Through neuroimaging, previous studies have shown that sensory deficits in one modality can cause amplified performance in sensory processing of other modalities in a phenomenon known as sensory compensation. This is often seen in people with extreme sensory deficits, such as people who suffer from deafness, those who experience a loss of auditory cues. However, not much is known about whether sensory … Continue reading Deaf People and Sensory Compensation

Bilinguals’ Ease of Lexical Access Related to the Switching of Languages

Sooraj Shah ’24 Over 43% of the United States population is bilingual and speaks more than one language. A skill fostered at a young age, bilingual speakers can converse and switch freely between multiple languages, but the root cause of why and when this occurs is not clear. A study conducted in Spain in collaboration with Stony Brook University’s Psychology Department explored the relationship between … Continue reading Bilinguals’ Ease of Lexical Access Related to the Switching of Languages

The Correlation Between Urinary Growth Factor and Brain Growth in Relation to Postnatal Development

Sooraj Shah ’24 Premature births occur in nearly 1 in every 10 cases in the United States, which can lead to numerous diverse health effects in the future. Two neurotrophic proteins which are responsible for the survival of neurons, Nerve Growth Factor(NGF) and Brain Derived Neurotrophic Factor(BDNF), are crucial for the development of the peripheral and central nervous systems. NGFs and BDNFs are critical for … Continue reading The Correlation Between Urinary Growth Factor and Brain Growth in Relation to Postnatal Development