Caption: Parent and child stress hormone levels may be bidirectionally concordant, with both influencing the other’s HPA axis activity.

Parent and child cortisol levels show concordance in certain conditions

Aaradhana Natarajan, 2020 The hypothalamus-pituitary-adrenal axis, or HPA axis, is a neuroendocrine pathway that is linked to emotional functioning and health. Researchers at the University of Maryland College Park, led by Dr. Stephanie Merwin, recently investigated whether or not the HPA axis functioning of a child showed correlation to that of their parents. They accounted for both the child’s temperament and parent’s psychological history in … Continue reading Parent and child cortisol levels show concordance in certain conditions

Caption: Gray matter is a crucial component of the human nervous system, and the location of synaptic connections. This is where thoughts are formed.

Perinatally acquired HIV associated with lower regional grey matter volume

Aaradhana Natarajan, 2020 The Human Immunodeficiency Virus, commonly called HIV, is one of the most widespread immune disorders across the globe. It weakens the immune system by reducing lymphocyte count and increasing susceptibility to other diseases. While it is most commonly known for its transmissibility, it is also possible for HIV-positive pregnant women to pass on the infection to their offspring. This form of HIV … Continue reading Perinatally acquired HIV associated with lower regional grey matter volume

Caption: Mice brains are similar to humans, with study results suggesting that sleep disturbances can lead to the formation of neurodegenerative plaques.

Sleep disturbances may play a role in Alzheimer’s pathogenesis

Aaradhana Natarajan, 2020 Alzheimer’s Disease is a neurodegenerative condition that has recently become a popular focus for research. As a result, scientists are now aware that the accumulation of amyloid-β-peptide oligomers (AβOs) play a central role in Alzheimer’s pathogenesis. However, the effect of sleep disturbances on Alzheimer’s risk is relatively underknown. This knowledge gap spurred Dr. Grasielle Kincheski and her team at the Federal University … Continue reading Sleep disturbances may play a role in Alzheimer’s pathogenesis

Research on the presence of carcinogenic compounds in Nigerian smoked fish

by Aaradhana Natarajan ’20 Smoked fish makes up nearly 61% of the dry fish produced in Nigeria. While smoking is a common technique for meat preservation, wood smoke typically produces Polycyclic aromatic compounds (PAHs), which then saturate the fish meat. Professor Isioma Tongo and researchers at the University of Benin in Nigeria studied the concentration of PAHs in four local species of smoked fish and … Continue reading Research on the presence of carcinogenic compounds in Nigerian smoked fish

Study examines the effect of exosomes on osteochondral regeneration

by Aaradhana Natarajan ’20 Adult mesenchymal stem cells (MSCs) are effective in osteoarithritic repair of bone cartilage. Currently, the efficacy of stem cell treatments has been ascribed to the exosomes released by the MSCs. Dr. Zhang and researchers at the National University of Singapore recently investigated the ability of MSC exosomes to treat osteochondral defects. Researchers created osteochondral defects on the trochlear grooves on the … Continue reading Study examines the effect of exosomes on osteochondral regeneration

Curcumin has the potential to alterations caused by ischemia

by Aaradhana Natarajan ’20 Ischemia can result when blood flow is severely reduced. The lack of sufficient oxygen and glucose causes cells to inflame as the body tries to regain homeostasis. Dr. Glaura Fernandes Teixeira de Alcântara and researchers at Estacio of Juazeiro da Norte in Brazil studied the neuroprotective ability of curcumin for global cerebral ischemia in the hippocampus. The researchers used a rat … Continue reading Curcumin has the potential to alterations caused by ischemia