Can Exercise Improve Chemotherapy Side-Effects?

Author: Amal Bilal, Class of 2028 Figure 1. Woman lifting two dumbbells at the gym Certain types of chemotherapy, a widely used treatment for cancers, can lead to chemotherapy-induced peripheral neuropathy (CIPN), a side-effect that causes pain, numbness, tingling, balance difficulties, and an increased risk of falls. Up to 68% of patients undergoing chemotherapy develop CIPN during or immediately after treatment, and 30-40% of patients … Continue reading Can Exercise Improve Chemotherapy Side-Effects?

Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse

By Riya Gandhi ‘22 Relapse of acute myeloid leukemia (AML) — or any type of cancer, for that matter — has always posed an enormous challenge to patients and physicians alike. However, a recent study conducted by researchers at McMaster University has found that it is not predominantly leukemic stem cells that induce such recurrence but rather leukemic-regenerating cells that arise post-chemotherapy. In this study, … Continue reading Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse

Focused Ultrasounds Increase Chemotherapy Drug Uptake

By Allan Mai ‘20 The blood-brain barrier (BBB) protects the brain from infections that enter through the bloodstream. However, this barrier also poses an enormous challenge for researchers developing drugs to specifically target the brain via the blood vessels. For brain tumors specifically, a current method for chemotherapy delivery are Gliadel Wafers: surgeons resect the tumor from the brain and fill the crater left behind … Continue reading Focused Ultrasounds Increase Chemotherapy Drug Uptake