Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse

By Riya Gandhi ‘22 Relapse of acute myeloid leukemia (AML) — or any type of cancer, for that matter — has always posed an enormous challenge to patients and physicians alike. However, a recent study conducted by researchers at McMaster University has found that it is not predominantly leukemic stem cells that induce such recurrence but rather leukemic-regenerating cells that arise post-chemotherapy. In this study, … Continue reading Malignant Regenerative Cells Induced by Chemotherapy: A Possible Cause of AML Relapse

Focused Ultrasounds Increase Chemotherapy Drug Uptake

By Allan Mai ‘20 The blood-brain barrier (BBB) protects the brain from infections that enter through the bloodstream. However, this barrier also poses an enormous challenge for researchers developing drugs to specifically target the brain via the blood vessels. For brain tumors specifically, a current method for chemotherapy delivery are Gliadel Wafers: surgeons resect the tumor from the brain and fill the crater left behind … Continue reading Focused Ultrasounds Increase Chemotherapy Drug Uptake