Tag: genome

2023-24, Cognition, Neuroscience

Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

Author: Vignesh Subramanian, Class of 2024 Figure 1: Increasing evidence suggests biological aging, measured by examining the extent of methylation of cells’ DNA, is a stronger predictor of diminishing cognitive abilities than chronological age.  Title: Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age Age acceleration is the term used to describe the difference between an individual’s chronological age, the length of time … Continue reading Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

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Disease, Health, Health and Medicine, Natural World

Viruses in Koalas Can Be Models for Genome Immunity

Ellie Teng ‘21 Retroviruses such as HIV are viruses that take genes from host cells and incorporate them into their own genomes. Transposons are DNA elements that can change positions in the genome, increasing the potential for mutations and genome instability. Piwi-interacting RNAs (piRNAs) guide the immune system towards silencing the transposons during germline development. Koalas infected by the retrovirus KoRV-A virus are immunodeficient and … Continue reading Viruses in Koalas Can Be Models for Genome Immunity

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2018-19

Using the Genome to Forecast Health

By Allan Mai ‘20 Wouldn’t it be convenient if researchers could tell how likely an individual is to have a certain disease just by looking at his or her genome? Researchers are doing exactly that by looking at over 6.6 million points of the human genome; according to Sekar Kathiresan, a geneticist at Massachusetts General Hospital (Mass General), scientists now have the ability to calculate … Continue reading Using the Genome to Forecast Health

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