Tag: dementia

2024-25, Cognition, Degenerative Disease, Disease, General Neuroscience, Health, Health and Medicine

Green Tea: Fighting Dementia One Cup at a Time

Sean Krivitsky, Class of 2026 Dementia is a progressive neurological disease most prevalent in older adults that is associated with aging and significant declines in cognitive function and memory. It has been strongly correlated with general brain atrophy, including of the hippocampus, and the increased presence of lesions (areas of damage within brain tissue) in cerebral white matter. This corresponds to the symptoms observed in … Continue reading Green Tea: Fighting Dementia One Cup at a Time

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Cellular and Molecular Science, Molecular Biology, Neuroscience

Diminished Glymphatic Transport and Lymphatic Drainage Tied to Cerebral Amyloid Angiopathy

Author: Vignesh Subramanian, Class of 2024 Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder characterized by the accumulation of amyloid protein deposits along cortical capillaries, cerebral vessel walls, and the brain’s leptomeninges. These plaques weaken fragile blood vessels, often resulting in intracerebral hemorrhaging. CAA is linked to vascular cognitive impairment and dysfunction and is a major contributor to the pathogenesis of Alzheimer’s disease (AD) and … Continue reading Diminished Glymphatic Transport and Lymphatic Drainage Tied to Cerebral Amyloid Angiopathy

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Neuroscience

Antipsychotics May Increase Risk of Dementia in Schizophrenic Patients

Vignesh Subramanian ’24 Schizophrenia is a psychotic disorder characterized by disorganized behavior, lack of emotional expression, and thoughts and experiences dissociated from reality. Patients who present such symptoms have elevated levels of the neurotransmitter dopamine, the ‘feel-good’ hormone responsible for mediating pleasure and stimulating neurons to carry out vital functions like concentration and motor control. Patients with schizophrenia are prescribed antipsychotic medications, which block binding … Continue reading Antipsychotics May Increase Risk of Dementia in Schizophrenic Patients

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Biology

Hearing Loss and Cognition: The Role of Hearing Aids, Social Isolation and Depression

Sabah Bari ’24 Individuals with hearing loss have been correlated with low cognitive functioning and incident dementia. Cognitive impairment includes problems with memory, having trouble with learning new tasks, concentrating or making decisions that affect their everyday life. Dementia is a form of cognitive impairment, in the sense of, loss of memory, language and problem solving. Both conditions can limit an individual’s function and interfere … Continue reading Hearing Loss and Cognition: The Role of Hearing Aids, Social Isolation and Depression

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General Neuroscience

World Trade Center first responders with PTSD and cognitive impairment at high-risk for developing dementia

Priyanshi Patel ’22 According to two studies presented by Stony Brook University at the Alzheimer’s Association International Conference, World Trade Center (WTC) first responders with signs of cognitive impairment (CI) exhibited neurological abnormalities and anomalies in their blood, which are normally attributed to Alzheimer’s disease patients. The first study investigated MRI results of WTC responders that showed significant gray matter atrophy compared to individuals of … Continue reading World Trade Center first responders with PTSD and cognitive impairment at high-risk for developing dementia

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2018-19

Elimination of Senescent-Expressing Genes Prevents Neurodegeneration

By Allan Mai ‘20 Much medical research is dedicated to the challenge of preventing the buildup of the proteins that cause diseases or accelerate their progression. Many researchers have devoted their careers to finding ways to prevent these diseases at the molecular level. One researcher and his colleagues are currently looking into senescent cells in hopes of finding answers on neurodegeneration which is the loss … Continue reading Elimination of Senescent-Expressing Genes Prevents Neurodegeneration

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