Dopamine Circuits: Investigating Relationships Between Dopamine Dysregulation and Midbrain Circuits

Daphne Siozios ’23 Dopamine (DA) is a behavioral neuromodulator that controls the function of the central nervous system through a variety of roles from memory processing and perception to learning and habit formation. The mesolimbic DA pathway, which travels specifically through the midbrain, has been linked to neural deficits caused by a lack of dopamine neurons in the striatum. While research regarding DA’s dysregulation has … Continue reading Dopamine Circuits: Investigating Relationships Between Dopamine Dysregulation and Midbrain Circuits

Can We Control Our Dopamine?

Aditi Kaveti ’23 Dopamine is a notorious molecule, with effects ranging from heightened sense of happiness and increased energy, to anxiety and difficulty sleeping. It is involved in cognitive processing related to reward and pleasure. Research into this molecule offers a wide range of study as scientists attempt to understand the dynamics and neuromodulation that occurs in the brain. Conrad Foo, a graduate student at … Continue reading Can We Control Our Dopamine?

Antipsychotics May Increase Risk of Dementia in Schizophrenic Patients

Vignesh Subramanian ’24 Schizophrenia is a psychotic disorder characterized by disorganized behavior, lack of emotional expression, and thoughts and experiences dissociated from reality. Patients who present such symptoms have elevated levels of the neurotransmitter dopamine, the ‘feel-good’ hormone responsible for mediating pleasure and stimulating neurons to carry out vital functions like concentration and motor control. Patients with schizophrenia are prescribed antipsychotic medications, which block binding … Continue reading Antipsychotics May Increase Risk of Dementia in Schizophrenic Patients

The Relationship Between Dopamine and Development of Asthma

Aditi Kaveti ‘23 Asthma is a chronic condition in the United States that affects more than 26 million people, including an estimated 6 million children. Asthma is described as an intermittent inflammation and narrowing of the airways in the lungs, wheezing, chest tightness, shortness of breath, and coughing. Inflammation is regulated by the nervous system which is regulated by the immune system. Harvard researcher Xingbin … Continue reading The Relationship Between Dopamine and Development of Asthma