Cryopreservation of semen without using egg yolk

Panayiota Siskos ’23 Cryopreservation of semen conserves genetic information and allows fertilization via artificial insemination. Egg yolk is an ingredient of bull semen extender, which buffers sperm from temperature and environmental stressors. However, egg yolk composition is very variable between different producers. Cholesterol is a molecule that strengthens membrane structures. Increasing cholesterol content in sperm plasma membrane increases cryotolerance, allowing sperm to survive freezing temperatures. … Continue reading Cryopreservation of semen without using egg yolk

Does Reward Responsivity Moderate or Mediate Effects of Parental Depression on Offspring?

Panayiota Siskos 2023 Figure 1: Depression alters the reward responsivity, and is described as having less tendency to adjust behavior or put in effort for rewards. Depression has alterations in reward responsiveness constructs with subjective experiences of pleasure and neural activation for rewarding. Alterations may be assessed with neurophysiological measures including reward positivity event-related potential which correlates with positive emotionality in kids, behavioral, and self-report … Continue reading Does Reward Responsivity Moderate or Mediate Effects of Parental Depression on Offspring?

Cryopreservation of semen without using egg yolk

Panayiota Siskos ’23 Cryopreservation of semen conserves genetic information and allows offspring to inherit the traits of genetically superior organisms via artificial insemination. Egg yolk is an ingredient of bull semen extender, a liquid diluent that acts as a buffer that protects sperm from changes in temperature and environmental conditions. However,  egg yolk is an ingredient that is hard to standardize due to variations between … Continue reading Cryopreservation of semen without using egg yolk

Can Immediate Gains in Single-Session Intervention Predict Long-Symptom Change?

Panayiota Siskos ’23 Single-session interventions (SSIs) for youth mental health problems show promise to prevent and reduce youth psychopathology and may be a good alternative to the more traditional multi-session ones that are inaccessible due to logistical and financial obstacles. However, SSIs may not be beneficial for everyone, and it is important to differentiate the needs of youths. Immediate gains, or improvements, in program-specific targets, … Continue reading Can Immediate Gains in Single-Session Intervention Predict Long-Symptom Change?

Genetic factors may be involved in disease risk of early-onset autoimmune thyroid disease

Panayiota Siskos ’23 Autoimmune thyroid diseases, such as Graves’ disease and Hashimoto’s disease, are often characterized by the infiltration of T cells and B cells in the thyroid as well as the production of antibodies specific to thyroid antigens. Genes including human leukocyte antigen (HLA), cytotoxic T lymphocyte-associated factor 4 (CTLA-4), CD40, and protein tyrosine phosphatase-22 (PTPN-22) have been previously associated with susceptibility to autoimmune … Continue reading Genetic factors may be involved in disease risk of early-onset autoimmune thyroid disease

Threatening cues have a larger effect on perception than neutral cues

Panayiota Siskos ’23 The theory of predictive coding states that the brain continuously creates a mental model of the surrounding environment using prior knowledge from memory. This mental model is then used to predict sensory input, such as anticipating a smell, a sound, or a touch.  A group of researchers from Stony Brook University and Columbia University studied the effect of threatening cues on sensory … Continue reading Threatening cues have a larger effect on perception than neutral cues