HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

Author: Sean Krivitsky, Class of 2026 Many have been led to believe that DNA contains all the information we need, but the regulation of the expression of genes encoded in DNA is also incredibly important. This differentiates humans from, for instance, gorillas, which otherwise share more than 98% genetic identity to humans. One level of regulation is at the level of chromatin, which results from … Continue reading HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

Natural Antifreeze: Insights into Animals’ Adaptations to Extreme Cold

Author: Sean Krivitsky, Class of 2026 Many organisms, like fish and insects, are capable of living in extreme conditions far outside of the viable range for humans. While some bacteria can live in hot geysers, others live in the extreme cold, relying on adaptations such as the expression of antifreeze proteins (AFP) to survive. These proteins help adapt to the cold by depressing the freezing … Continue reading Natural Antifreeze: Insights into Animals’ Adaptations to Extreme Cold

Tiny Plastics, Big Impact: How Microplastics Affect Earthworms and Soil Health

Author: Diego Javier, Class of 2026 A concern that is emerging worldwide is plastic contamination in agricultural soils. Farmers frequently use plastic mulching films in order to improve crop yields and control weeds. However, these films can break down into tiny fragments, called microplastics, which are then ingested by soil organisms like earthworms and can affect soil health. In order to better understand these effects, … Continue reading Tiny Plastics, Big Impact: How Microplastics Affect Earthworms and Soil Health

Watching Muscles Heal: A Zebrafish Model for Regeneration

Author: Diego Javier, Class of 2026 Muscle regeneration is a nuanced and important area of study in understanding how muscles recover from injury. Researchers have been trying to develop therapies for muscle-related diseases, and some have used zebrafish as a model organism given their ability to regenerate their heart and skeletal muscles. In order to study muscle regeneration. Eric Paulissen, in the lab of SBU … Continue reading Watching Muscles Heal: A Zebrafish Model for Regeneration

GlycoSwitch: Signaling Tuner O-Glucosylation 

Author: Sajia Athai, Class of 2026 Looking through URECA presentations every year, posters detailing scientific protocols and findings of undergraduate students cover the corners of the room.  Undergraduate Advisor for Biochemistry and Animal Development Professor, Dr. Bernadette Holdener, leads her team of mentees in understanding how protein O-glucosyltransferase 2 and 3 (POGLUT2/3) is integral to separation of digits during limb development in mice.  Dr. Holdener’s … Continue reading GlycoSwitch: Signaling Tuner O-Glucosylation 

Genome Grazing: lcWGS Across Livestock and Agricultural Landscapes

Author: Sajia Athai, Class of 2026 Just as cells comprise the fundamental units that make up an organism, livestock acts as the core of agriculture—anchoring growth across the world. As providers of food security to sustainability, livestock is an integral part of economic prosperity and animal diversity. Livestock is assessed on measures in the agricultural industry such as disease screening, mobility, fertility, and birth weight. … Continue reading Genome Grazing: lcWGS Across Livestock and Agricultural Landscapes

Decoding the Lon Enzyme’s Protein Recognition Code

Author: Antonia Truta, Class of 2028 Lon protease is an important enzyme within the mitochondria’s inner membrane. This enzyme specifically regulates protein homeostasis, meaning it helps keep the protein levels within the cell balanced. The Lon protease acts by breaking down damaged or misfolded proteins that lack proper structure to function correctly and may harm the cell. Lon also degrades certain regulatory proteins whose levels … Continue reading Decoding the Lon Enzyme’s Protein Recognition Code

Neurogenesis and Repair Mechanisms Following Traumatic Brain Injury: Insights from Mouse Models

Kang Lai, Class of 2026 Traumatic Brain Injury (TBI) is one of the most common causes of cognitive defects affecting both physical and mental functions of the brain. Its implications span from cognitive defects to motor dysfunction to behavioral disorders–all of which permanently and severely diminish quality of life. TBI also greatly disrupts neurogenesis–the formation of new neurons– and neuronal stem cell regeneration. At the … Continue reading Neurogenesis and Repair Mechanisms Following Traumatic Brain Injury: Insights from Mouse Models

Biochemical Mechanisms Behind the Sleep-Promoting Effects of Bananas and Milk

Kang Lai, Class of 2026 Sleep is an important controlling factor of many regulatory and restorative functions of the human body. However, many conditions have impacted sleep quality, the most prevalent being insomnia. A study conducted by Dr. Muteber Gizen Keser and colleagues at KTO Karatay University examined certain biochemical parameters and behavioral analyses to determine whether banana and milk lead to the improved sleep … Continue reading Biochemical Mechanisms Behind the Sleep-Promoting Effects of Bananas and Milk

Unraveling Long COVID: The Silent Impact of Reinfection

Tiffany Ang, Class of 2026 Post-acute sequelae of COVID-19 (PASC), or “Long COVID,” refers to ongoing or new symptoms that persist at least three months after a SARS-CoV-2 infection. Common symptoms include chest pain, cognitive dysfunction, shortness of breath, brain fog, headache, and fatigue. A study by Dr. Luft from Stony Brook University investigated the association between SARS-CoV-2 re-infection and the incidence of PASC among … Continue reading Unraveling Long COVID: The Silent Impact of Reinfection

Linking Stress with Poor Cancer Prognosis

Sean Krivitsky, Class of 2026 Stress is a common response many experience amidst various physical, emotional, or psychological challenges. Beyond its significant short-term impacts, chronic stress has been demonstrated to impact cognitive function as well as the health of various systems within the body, including the immune system. Cancer patients in particular often fall victim to chronic stress, which, in turn, has been associated with … Continue reading Linking Stress with Poor Cancer Prognosis

Flavonoids to the Rescue: Combating Age-Related Neurodegeneration

Sean Krivitsky, Class of 2026 Neurodegeneration, which is often associated with aging, leads to the development of serious diseases, including Alzheimer’s disease and Parkinson’s disease, that afflict more than 50 million people worldwide. In addition to their devastating impact, neurodegenerative diseases are particularly problematic regarding their prognosis, diagnosis, and treatment. One of the primary factors underlying the development of neurodegenerative diseases is mitochondrial dysfunction. This … Continue reading Flavonoids to the Rescue: Combating Age-Related Neurodegeneration