Category: Cellular and Molecular Science

Biology, physiology, YIWC 2025

Translational Biology – Anthony Guidi

Imagine walking into a store and being handed a single shirt labeled “one size fits all.” Chances are, it wouldn’t fit you perfectly. Yet, this is essentially how traditional healthcare treats patients, providing the same treatments to everyone, despite biological differences that can lead to drastic changes in medical needs. Personalized and precision medicine seeks to revolutionize healthcare by customizing treatments to each person’s distinct … Continue reading Translational Biology – Anthony Guidi

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Biology, Cellular and Molecular Science, Genetics, Molecular Biology, physiology

HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

Author: Sean Krivitsky, Class of 2026 Many have been led to believe that DNA contains all the information we need, but the regulation of the expression of genes encoded in DNA is also incredibly important. This differentiates humans from, for instance, gorillas, which otherwise share more than 98% genetic identity to humans. One level of regulation is at the level of chromatin, which results from … Continue reading HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

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Biology, Cellular and Molecular Science, Genetics, Molecular Biology

Natural Antifreeze: Insights into Animals’ Adaptations to Extreme Cold

Author: Sean Krivitsky, Class of 2026 Many organisms, like fish and insects, are capable of living in extreme conditions far outside of the viable range for humans. While some bacteria can live in hot geysers, others live in the extreme cold, relying on adaptations such as the expression of antifreeze proteins (AFP) to survive. These proteins help adapt to the cold by depressing the freezing … Continue reading Natural Antifreeze: Insights into Animals’ Adaptations to Extreme Cold

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Biology, Ecology, Environment, Molecular Biology

Tiny Plastics, Big Impact: How Microplastics Affect Earthworms and Soil Health

Author: Diego Javier, Class of 2026 A concern that is emerging worldwide is plastic contamination in agricultural soils. Farmers frequently use plastic mulching films in order to improve crop yields and control weeds. However, these films can break down into tiny fragments, called microplastics, which are then ingested by soil organisms like earthworms and can affect soil health. In order to better understand these effects, … Continue reading Tiny Plastics, Big Impact: How Microplastics Affect Earthworms and Soil Health

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Biology, Cellular and Molecular Science, Disease, Health, Medicine and Physiology, Molecular Biology

Watching Muscles Heal: A Zebrafish Model for Regeneration

Author: Diego Javier, Class of 2026 Muscle regeneration is a nuanced and important area of study in understanding how muscles recover from injury. Researchers have been trying to develop therapies for muscle-related diseases, and some have used zebrafish as a model organism given their ability to regenerate their heart and skeletal muscles. In order to study muscle regeneration. Eric Paulissen, in the lab of SBU … Continue reading Watching Muscles Heal: A Zebrafish Model for Regeneration

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Biology, Cellular and Molecular Science, Embryonic Development, Molecular Biology

GlycoSwitch: Signaling Tuner O-Glucosylation 

Author: Sajia Athai, Class of 2026 Looking through URECA presentations every year, posters detailing scientific protocols and findings of undergraduate students cover the corners of the room.  Undergraduate Advisor for Biochemistry and Animal Development Professor, Dr. Bernadette Holdener, leads her team of mentees in understanding how protein O-glucosyltransferase 2 and 3 (POGLUT2/3) is integral to separation of digits during limb development in mice.  Dr. Holdener’s … Continue reading GlycoSwitch: Signaling Tuner O-Glucosylation 

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Biology, Cellular and Molecular Science, Genetics, Molecular Biology

Genome Grazing: lcWGS Across Livestock and Agricultural Landscapes

Author: Sajia Athai, Class of 2026 Just as cells comprise the fundamental units that make up an organism, livestock acts as the core of agriculture—anchoring growth across the world. As providers of food security to sustainability, livestock is an integral part of economic prosperity and animal diversity. Livestock is assessed on measures in the agricultural industry such as disease screening, mobility, fertility, and birth weight. … Continue reading Genome Grazing: lcWGS Across Livestock and Agricultural Landscapes

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Biology, Cellular and Molecular Science, Chemistry

Decoding the Lon Enzyme’s Protein Recognition Code

Author: Antonia Truta, Class of 2028 Lon protease is an important enzyme within the mitochondria’s inner membrane. This enzyme specifically regulates protein homeostasis, meaning it helps keep the protein levels within the cell balanced. The Lon protease acts by breaking down damaged or misfolded proteins that lack proper structure to function correctly and may harm the cell. Lon also degrades certain regulatory proteins whose levels … Continue reading Decoding the Lon Enzyme’s Protein Recognition Code

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Exercise, Health, Health and Medicine, physiology

Whiskers, Weight, and Wheat: Is it the Carbs?

Author: Sajia Athai, Class of 2026 Walking through the streets of the city, every New Yorker knows the best spots: the thrift stores, the restaurants, parking lots to chill at, but most importantly, the cat cafes. Everyone loves cats, especially the big, cute, and fluffy ones. With cat videos always going viral across the country, viewers are often quick to judge the health of seemingly … Continue reading Whiskers, Weight, and Wheat: Is it the Carbs?

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Ecology, Health, Natural World, physiology

The Ethics of Animal Use in Research

Author: Antonia Truta, Class of 2028 Is the use of animals in research for human benefit morally justified? If so, how can experiments maintain ethical integrity while still advancing scientific goals? Professor Marcel Mertz at Hannover Medical School and a diverse range of colleagues, including scientists, philosophers, and legal scholars, explore these questions with a focus on animal models in research. The emerging field of … Continue reading The Ethics of Animal Use in Research

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2024-25, Cellular and Molecular Science, Molecular Biology

Cysteine-Rich γ-Crystallins Evolutionary Role in Lens Transparency and Function

Eimaan Bilal, Class of 2028 Cysteine (Cys) is a sulfur-containing amino acid found in crystallin proteins that compose our eye’s lens. When Cys is oxidized, it can lead to crystallin protein misfolding and unwanted disulfide bonding, causing light-scattering aggregation. Light-scattering aggregation in crystallin proteins is one of the main contributors to cataract disease, which clouds the lens and can even develop into blindness. Since Cys … Continue reading Cysteine-Rich γ-Crystallins Evolutionary Role in Lens Transparency and Function

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2024-25, Genetics, Molecular Biology, physiology

Osmotic Stress Alters Circadian Rhythm

Asher Agarwal, Class of 2027 The circadian rhythm regulates many physiological processes via transcriptional feedback loops involving proteins such as Bmal1 and Clock. Circadian rhythm is closely tied to cell-cycle progression, and disruptions in one can affect the other. Hypoosmotic stress causes water to rush into a cell, triggering changes in gene regulation to adapt to the stress. Caveolae, protein invaginations in the cell membrane, … Continue reading Osmotic Stress Alters Circadian Rhythm

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