Category: Cancer

Cancer

Breast Cancer Metastasis Hypothesized to be Affected by Type of Administered Anesthesia

Simran Kaur ‘20 Complete surgical resection of breast tissue, known as a mastectomy, is often suggested as the first-line treatment in patients diagnosed with breast cancer. Metastasis, the spread of cancer cells to other parts of the body, is a frequent occurrence after surgery and is the primary cause of cancer-related deaths. It was hypothesized by the researchers in this study that the type of … Continue reading Breast Cancer Metastasis Hypothesized to be Affected by Type of Administered Anesthesia

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Cancer

Nanoparticles May Be the New Future for Cancer Immunotherapy

Gaurav Sharma ’22 Cancer immunotherapy has been extensively explored and requires information of the tumor’s antigen presentation in order for a method to be selected. An approach that is more effective and has a broader range had not been found that did not have the constraint of needing the information of the tumor’s antigen presentation. Researchers at Johns Hopkins School of Medicine and Johns Hopkins … Continue reading Nanoparticles May Be the New Future for Cancer Immunotherapy

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Cancer, Cellular and Molecular Science

Inactivated Gene Linked to Kidney Cancer and Tumor Development in Mice

Gaurav Sharma ’22 The epigenetic components pertaining to the onset of cancer have been of interest for many years due to the hope of developing approaches to delay the onset of cancer in the future for an individual. Recently, a tumor suppressor family has been discovered, called Ras-Association Domain Family (RASSF) which epigenetically inactivated breast, lung, skin, and thyroid cancers. Neither RASSF10’s in-vivo function nor … Continue reading Inactivated Gene Linked to Kidney Cancer and Tumor Development in Mice

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Cancer, General Neuroscience

After the Fall: Link Between PTSD and Prostate Cancer

Wendy Wu ’22 On the morning of September 11, 2001, the Twin Towers of the World Trade Center (WTC) collapsed. Within minutes, first responders arrived on the scene. Amidst the debris and smothering dust, they got to work, evacuating citizens and heading into the towers to rescue whoever they could. It was truly a display of heroic bravery and compassion, but unfortunately, many of the … Continue reading After the Fall: Link Between PTSD and Prostate Cancer

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Cancer, Health, Health and Medicine

Application of Trispecific Antibodies to Anticancer Immunotherapy

Ashley Goland ’23 Immunotherapy is a form of cancer treatment that utilizes the body’s own immune system to destroy cancerous tumors and has shown promise in past animal and clinical human trials. For all of its dazzling successes to date, however, immunotherapy is not completely effective for treating the full range of cancer types and patients— yet. Scientists working in Sanofi Research and Development believe … Continue reading Application of Trispecific Antibodies to Anticancer Immunotherapy

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Cancer, Cellular and Molecular Science, Health and Medicine, Medicine and Physiology

Different Types of Anesthesia can Impact Breast Cancer Metastasis.

Priyanshi Patel ‘22 Metastasis refers to the surgical removal of solid tumors and metastasis is the main cause of cancer death. Previously, not much was known about the role anesthetics play in cancer metastasis. Complete surgical removal of solid tumors offers the possibility of a cure and is the basic treatment provided. Despite surgery, recurrent metastasis in vital organs does reoccur and is a major … Continue reading Different Types of Anesthesia can Impact Breast Cancer Metastasis.

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Cancer, Disease, Health and Medicine, Pharmacology

Improved Body Composition After Testosterone Treatment in Young Male Cancer Survivors

Priyanshi Patel ’22 Young male cancer survivors have low testosterone levels compared to those of  healthy populations. Long term effects of low testosterone involve endocrine disorders that affect up to 50% of adult childhood cancer survivors, and younger survivors are often unsure as to whether they would benefit from testosterone treatment. A study was conducted in the United Kingdom on secondary hospital outpatients.. The study … Continue reading Improved Body Composition After Testosterone Treatment in Young Male Cancer Survivors

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Biology, Cancer, Health and Medicine

Biodiversity Offers Insight into the Ecosystem of Liver Cancer

Priyanshi Patel ’22 Liver cancer is the second most lethal malignancy in the world and includes mainly hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). HCC is the most common type of primary liver cancer and often occurs in people with chronic liver diseases. iCCA is also a cancer that develops within the bile duct, whereas HCC occurs among alcoholics or those with fat accumulation in … Continue reading Biodiversity Offers Insight into the Ecosystem of Liver Cancer

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Cancer, Health and Medicine, Medicine and Physiology

Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

Jorge Pincay ’20 Phosphoglycerate mutase 1 (PGAM1) is a gene known to promote rapid tumor growth and invasiveness in several cancers, including non-small cell lung cancer (NSCLC). PGAM1 encodes for an enzyme that catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate in the glycolytic pathway,  a compound that coordinates anabolic biosynthesis. In many forms of cancer, including NSCLC, urothelial bladder cancer, and hepatocellular carcinoma, upregulation of … Continue reading Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

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Cancer, Disease, Medicine and Physiology

Common Fungi May Drive Pancreatic Cancer

Nicole Zhao ’20 Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide and occurs more frequently in developed countries (1). What makes pancreatic cancer even more alarming is that patients seldom exhibit symptoms until an advanced stage of the disease when little can be done for them (1). Therefore, techniques in early detection and risk assessment are crucial in the prognosis of a … Continue reading Common Fungi May Drive Pancreatic Cancer

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Cancer, Health and Medicine

The Association Between Coffee Products and Breast Cancer Risk in Hong Kong

Ayesha Azeem ‘23 In women, breast cancer is universally seen as the most common cancer, with diet being one of the most important factors in causing the condition. Coffee is one of the most popular drinks available in the world and, in Hong Kong, a recent fan-favorite. From 2010 to 2018, coffee revenue skyrocketed from 119 million USD to 279 million USD. With the obvious … Continue reading The Association Between Coffee Products and Breast Cancer Risk in Hong Kong

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Cancer

Sugary Drinks Increase Risk of Cancer

Ellie Teng ‘21 Added sugars were long known to have adverse health benefits, but sugary drinks were recently found to be linked to cancer. An increase in the consumption of sugary drinks the past decade is associated with the increase in obesity, which is a risk factor for various cancers. In France, a group of researchers assessed the connection between  the consumption of sugary drinks … Continue reading Sugary Drinks Increase Risk of Cancer

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