Amyloid-beta Deposition: A Cause or Byproduct of Alzheimer’s?

Author: Farzad Hoque, Class of 2028 The relationship between neurovascular coupling and Alzheimer’s disease (AD) progression has been a focal point of neurological research. While vascular dysfunction in AD is well-documented, questions remain about whether these abnormalities emerge before amyloid-beta (Aβ) deposition or arise as a consequence. Recent research has shed light on the early neurovascular changes in mouse models of AD, suggesting new mechanisms … Continue reading Amyloid-beta Deposition: A Cause or Byproduct of Alzheimer’s?

Uncovering a Novel Biomarker For The Identification of Parkinson’s-Related Diseases

Author: Sean Krivitsky, Class of 2026 Parkinson’s disease is a severe neurodegenerative disorder most commonly occurring in late adulthood. It is primarily characterized by motor dysfunctions such as uncontrollable tremors and stiffness. Since there is no conclusive test for diagnosis of the disorder, neurologists rely on a comprehensive evaluation system, combining symptoms and physical assessments to gauge the likelihood that an individual has Parkinson’s. A … Continue reading Uncovering a Novel Biomarker For The Identification of Parkinson’s-Related Diseases

Linking Key Immune System Components to Cancer Progression

Author: Sean Krivitsky, Class of 2026 Breast cancer is the most frequently diagnosed form of cancer in the world and is one of the leading causes of cancer-related deaths. Triple-negative breast cancer (TNBC), a common type of breast cancer, is fast-growing and is associated with consistent poor prognosis. Unlike several other types of breast cancer, TNBC possesses a unique pathogenic mechanism, which means that it … Continue reading Linking Key Immune System Components to Cancer Progression

Bupropion as a Possible Treatment for COVID-19-Related Brain Fog

Jessica George ’24 The COVID-19 pandemic has affected millions of people worldwide, and many have reported persistent symptoms even after recovery from the initial infection. One of the most common long-term symptoms reported is “brain fog,” a condition characterized by cognitive impairments such as memory loss, difficulty concentrating, and mental fatigue. A recent case series published by Dr. Samuel Reinfeld from the Stony Brook University … Continue reading Bupropion as a Possible Treatment for COVID-19-Related Brain Fog

Past Pandemics May Play a Role in Susceptibility to Disease

Melanie Karniewich ’25 When the human body reacts to something foreign, the immune response will likely ensure that the human body is unharmed. For example, when receiving a vaccine, the body remembers the virus being injected and will know how to fight it off the next time. A recent study identified traces of immune genes associated with the Black Death from the 1300s in current … Continue reading Past Pandemics May Play a Role in Susceptibility to Disease

Usage of Music Therapy on Anxiety-Presenting COVID-19 Patients

Sooraj Shah ’24 A rise in chronic respiratory and cardiac ailments has been attributed to the coronavirus pandemic. However, one overlooked consequence of COVID-19 is isolation, which increases the risk of developing stress-related disorders, such as anxiety and depression, as patients ponder whether separation is permanent. Previous research supports music as an important tool in addressing this psychological distress, as it has been shown to … Continue reading Usage of Music Therapy on Anxiety-Presenting COVID-19 Patients

Loss of Sense of Smell Caused by COVID-19

Aditi Kaveti ‘23 The coronavirus pandemic has changed our lifestyles as we knew it. As we find ways to stay safe during the pandemic, research continues to bring us new information about COVID-19. One of the earliest and most commonly reported indicators of COVID-19 is the temporary loss of smell, or anosmia. Olfactory cells are the body’s smell nerve cells that are stimulated by the … Continue reading Loss of Sense of Smell Caused by COVID-19

Low-Level Mechanical Signaling to Stimulate Bone Growth

Aditi Kaveti ’23 Osteoporosis is a disease characterized by the reduction of bone quality and low bone mineral density (BMD). Bone resorption is the process by which osteoclasts break down bone tissue and release minerals, resulting  in a transfer of calcium from bone tissue to blood. When excessive resorption occurs, bones weaken and become brittle, which may eventually develop into osteoporosis. Bone health can be … Continue reading Low-Level Mechanical Signaling to Stimulate Bone Growth

The Future of COVID-19 Testing

Wendy Wu ’22 COVID-19 is a disease caused by a newly discovered coronavirus: SARS-CoV-2. First identified in Wuhan, China in late 2019, the coronavirus disease has become a pandemic within a matter of months, causing worldwide panic and hysteria. In this short time, nations and the World Health Organization struggled to contain the outbreak. In addition to treatment and vaccines, developing a test for COVID-19 … Continue reading The Future of COVID-19 Testing

Higher Education Correlates to Later Onset of Alzheimer’s

Priyanshi Patel ‘22 Professors including Sean Clauston, Dylan Smith, and many others of the Public Health and Department of Family, Population, and Preventative program at Stony Brook University wanted to examine the association between education and the incidence of accelerated cognitive decline. Alzheimer’s disease and related dementias (ADRD) affect 5.4 million people in the United States and are the cause of the fifth most common … Continue reading Higher Education Correlates to Later Onset of Alzheimer’s

Opioid Poisoning Rates on Long Island

Ayesha Azeem ‘23 The United States currently faces a growing opioid poisoning crisis. Opioid use can lead to significant impairment and distress, social problems, chronic relapsing abuse and even early death. According to the National Center for Health Statistics, New York is one of 5 states with the most opioid drug overdoses. Historically, those affected by nonfatal opioid poisoning tend to be white males, aged … Continue reading Opioid Poisoning Rates on Long Island

Chloroquine as a Promising Anti-Viral Drug in Immunocompromised Patients Amidst the COVID-19 Pandemic

Simran Kaur ‘20 SARS-CoV-2, a new type of coronavirus, is responsible for a global pandemic that currently has infected hundreds of thousands of individuals worldwide. The virus belongs to the same family of viruses responsible for certain cases of the common cold, Middle East Respiratory Syndrome, and Sudden Acute Respiratory Syndrome (SARS). The virus is incredibly contagious, spreading through respiratory droplets and exploiting commonly-found human … Continue reading Chloroquine as a Promising Anti-Viral Drug in Immunocompromised Patients Amidst the COVID-19 Pandemic