Coenzyme Q10 Has Protective Effects in Alzheimer’s Disease

By Natalie Lo ‘21 Alzheimer’s Disease (AD) is the most prevalent type of dementia with links to memory impairment and behavioral issues in those diagnosed. Although the cause of AD is unknown, molecular characteristics of the disease include the growth of β-amyloid oligomers, which form plaques that result in brain atrophy. Previous studies have shown that oxidative stress plays a role in the pathogenesis of … Continue reading Coenzyme Q10 Has Protective Effects in Alzheimer’s Disease

Elimination of Senescent-Expressing Genes Prevents Neurodegeneration

By Allan Mai ‘20 Much medical research is dedicated to the challenge of preventing the buildup of the proteins that cause diseases or accelerate their progression. Many researchers have devoted their careers to finding ways to prevent these diseases at the molecular level. One researcher and his colleagues are currently looking into senescent cells in hopes of finding answers on neurodegeneration which is the loss … Continue reading Elimination of Senescent-Expressing Genes Prevents Neurodegeneration

The Use of CRISPR/Cas9 Gene Editing Tool in Treating Early Onset Alzheimer’s Disease

Stephanie Budhan ‘20 Early-onset Alzheimer’s disease (AD) is dominantly inherited genetic disorder that causes the development of Alzheimer’s Disease in individuals younger than 65 years old. AD is caused by a point mutation in three major genes, one of which is amyloid precursor protein (APP). APP is cleaved to generate beta amyloid which makes up the amyloid plaque found in the brains of AD patients. … Continue reading The Use of CRISPR/Cas9 Gene Editing Tool in Treating Early Onset Alzheimer’s Disease

Figure 1. New research suggests that the long-term effects of high intensity exercise extend to memory.

High Intensity Exercise Stimulates Memory

By Meenu Johnkutty ‘21 New research suggests that the long-term effects of high intensity exercise may prove to be more beneficial than previously thought. Many studies have demonstrated that aerobic exercise improves the structure and function of the hippocampus, the region of the brain responsible for learning and memory. Scientists posit that neurotrophic factors like insulin growth factor (IGF) and brain-derived neurotrophic factor (BDNF) are … Continue reading High Intensity Exercise Stimulates Memory

Chromosomal Studies Lead to Advancements for Alzheimer’s Disease

by Sahil Rawal (’19) Alzheimer’s disease is a well-known neurodegenerative disease that commonly affects people of older age. Although scientists have been able to connect different lifestyle factors with the onset of Alzheimer’s, the basic molecular mechanisms are still not completely understood. Currently, there are many ongoing studies that aim to gain more information on Alzheimer’s disease and the etiologies behind the devastating disease. Studies … Continue reading Chromosomal Studies Lead to Advancements for Alzheimer’s Disease