Tag: fa2025

Biology, Cellular and Molecular Science, Genetics, Molecular Biology, physiology

HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

Author: Sean Krivitsky, Class of 2026 Many have been led to believe that DNA contains all the information we need, but the regulation of the expression of genes encoded in DNA is also incredibly important. This differentiates humans from, for instance, gorillas, which otherwise share more than 98% genetic identity to humans. One level of regulation is at the level of chromatin, which results from … Continue reading HP1𝛼: How DNA Unwrapping can Support Heterochromatin Maintenance

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Biology, Cellular and Molecular Science, Embryonic Development, Molecular Biology

GlycoSwitch: Signaling Tuner O-Glucosylation 

Author: Sajia Athai, Class of 2026 Looking through URECA presentations every year, posters detailing scientific protocols and findings of undergraduate students cover the corners of the room.  Undergraduate Advisor for Biochemistry and Animal Development Professor, Dr. Bernadette Holdener, leads her team of mentees in understanding how protein O-glucosyltransferase 2 and 3 (POGLUT2/3) is integral to separation of digits during limb development in mice.  Dr. Holdener’s … Continue reading GlycoSwitch: Signaling Tuner O-Glucosylation 

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Disease, Health, Health and Medicine, Medicine and Physiology

Mild Gut Inflammation Can Impact the Developing Brain

Author: Diego Javier, Class of 2026 Figure 1. X-Ray of a newborn with highlight regions displaying areas affected by NEC Necrotizing enterocolitis (NEC) is an intestinal disease that affects around 10% of premature infants in the United States, resulting in either infant mortality or long-term developmental problems such as learning disabilities and behavioral problems in babies that do survive. While it is known that severe … Continue reading Mild Gut Inflammation Can Impact the Developing Brain

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Exercise, Health, Health and Medicine, physiology

Whiskers, Weight, and Wheat: Is it the Carbs?

Author: Sajia Athai, Class of 2026 Walking through the streets of the city, every New Yorker knows the best spots: the thrift stores, the restaurants, parking lots to chill at, but most importantly, the cat cafes. Everyone loves cats, especially the big, cute, and fluffy ones. With cat videos always going viral across the country, viewers are often quick to judge the health of seemingly … Continue reading Whiskers, Weight, and Wheat: Is it the Carbs?

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Brain, Cognition, Degenerative Disease, General Neuroscience, Neurology

Hippocampal interneuron activity drives functional hyperemia leading to neurovascular disfunction and Alzheimer’s Disease

Author: Kang Lai, Class of 2026 Functional hyperemia, or the dilation of blood vessels in response to increased metabolic activity, is critical for regulating the levels of oxygen and glucose in the brain. Moreover, it facilitates the clearance of metabolic byproducts such as amyloid-β peptide (Aβ), an accumulation of which underlies Alzheimer’s disease. In Alzheimer’s Disease (AD), disruptions in vascular dynamics are significant but poorly … Continue reading Hippocampal interneuron activity drives functional hyperemia leading to neurovascular disfunction and Alzheimer’s Disease

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