Figure 1. Scientists strive to create wearable smart devices that can detect physiological phenomena in real time. According to a study from UC Berkeley, new ear devices can be 3D printed and used to indicate patients’ true body temperatures.

3D-Printed Ear Devices Detect Core Body Temperature

By Caleb Sooknanan ’20 Healthcare sensors are frequently used to detect skin temperature, but more research is needed to design a device that can pinpoint core body temperature levels and help doctors predict the likelihood of fever, fatigue, and other physiological phenomena. Professor Ali Javey and researchers at the University of California, Berkeley designed a printable smart device that — when placed on a patient’s … Continue reading 3D-Printed Ear Devices Detect Core Body Temperature

Figure 1. Human gut microbe, P. histicola has therapeutic effects against Multiple Sclerosis (MS)

Gut microbe as Potential Treatment for Multiple Sclerosis

By Rideeta Raquib ’19 The human gut is colonized by many microorganisms and each of them plays a role in maintaining various physiological functions, such as regulating digestion and fat absorption. It has been found that a vast number of inflammatory diseases around the world are associated with an instability of the gut microbiome. Researchers at the Mayo Clinic and University of Iowa suggest that … Continue reading Gut microbe as Potential Treatment for Multiple Sclerosis

Figure 1. Zika vaccine developed from Nicotiana benthamiana plant extract

Improved Zika Vaccine Produced by Tobacco Plant extract

By Rideeta Raquib ’19 The Zika virus (ZIKV) is a deadly virus transmitted through mosquito bites that at its climax has infected more than 1.5 million people in Brazil in 2015. The virus continues to spread with approximately 200 ZIKV cases reported in the United States this year. In order to combat the epidemic, new ZIKV vaccines have been developed to inactivate the virus. However, … Continue reading Improved Zika Vaccine Produced by Tobacco Plant extract

Figure 1 A protein involved in malaria development identified

Novel Findings to Tackle Malaria

By Rideeta Raquib ’19 Malaria is a deadly disease caused by single-celled parasites of the genus Plasmodium. Once the body is infected, sporozoites migrate to the liver and replicate to merozoites. A sporozoite in a motile, sporelike phase during a parasite’s asexual reproduction. A merozoite is the growth stage, which occurs in the bloodstream. The toxins released by merozoites destroy red blood cells and can … Continue reading Novel Findings to Tackle Malaria

Caption: Parent and child stress hormone levels may be bidirectionally concordant, with both influencing the other’s HPA axis activity.

Parent and child cortisol levels show concordance in certain conditions

Aaradhana Natarajan, 2020 The hypothalamus-pituitary-adrenal axis, or HPA axis, is a neuroendocrine pathway that is linked to emotional functioning and health. Researchers at the University of Maryland College Park, led by Dr. Stephanie Merwin, recently investigated whether or not the HPA axis functioning of a child showed correlation to that of their parents. They accounted for both the child’s temperament and parent’s psychological history in … Continue reading Parent and child cortisol levels show concordance in certain conditions

Caption: Mice brains are similar to humans, with study results suggesting that sleep disturbances can lead to the formation of neurodegenerative plaques.

Sleep disturbances may play a role in Alzheimer’s pathogenesis

Aaradhana Natarajan, 2020 Alzheimer’s Disease is a neurodegenerative condition that has recently become a popular focus for research. As a result, scientists are now aware that the accumulation of amyloid-β-peptide oligomers (AβOs) play a central role in Alzheimer’s pathogenesis. However, the effect of sleep disturbances on Alzheimer’s risk is relatively underknown. This knowledge gap spurred Dr. Grasielle Kincheski and her team at the Federal University … Continue reading Sleep disturbances may play a role in Alzheimer’s pathogenesis

Figure 1: Defensiveness is a common symptom of ASD, manifesting in anxiety, social deficits, or other behavioral and psychological symptoms.

A Potential Mechanism Explaining Tactile Defensiveness in Autism

By Anna Tarasova ’19 Hypersensitivity to sensory stimuli is frequently an aspect of autism spectrum disorders (ASD), and can lead to defensiveness against touch and other sensory stimuli. This can contribute to hyperactivity and lead to inattention, learning difficulties, sleep disturbances, anxiety, and many other symptoms of autism. Although the mechanism of this phenomenon has long been unknown, Dr. Cynthia He and her colleagues at … Continue reading A Potential Mechanism Explaining Tactile Defensiveness in Autism

Figure 1: Fetus at 9-10 weeks estimated gestational age (EGA)

New Discoveries in Fetal Immune Response Capacity

By Anna Tarasova ’19 The immune system of a fetus differs significantly from that of an infant or adult. During the second trimester of pregnancy, a fetus’s immune system is able to recognize antigens, or foreign cells, and conduct an immune response using dendritic cells. Dendritic cells are antigen-presenting cells (APC), which means that they place antigens along with specific receptors on their cell surface … Continue reading New Discoveries in Fetal Immune Response Capacity

Figure 1: Oleic acid, found in olive oil, plays a role in cancer prevention.

Compound Found In Olive Oil Found to Prevent Cancer

By Rideeta Raquib MicroRNAs or miRs are small non-coding RNAs that guide gene regulation, such as the expression of their target mRNAs in a complex with ribucleoproteins called miRNPs. Inhibition of translation or a decrease in mRNA can cause miR-mediated downregulation of gene expression. Deregulation of microRNAs is associated with development of pathological illnesses including cancer. A potential tumor suppressor, miR-7, is regulated at both … Continue reading Compound Found In Olive Oil Found to Prevent Cancer

Figure 1: Infant teeth were used as biomarkers to analyse metal exposure and its connection to autism.

Infant Teeth Reveal Metal Exposure Correlates with Autism

By Rideeta Raquib Autism spectrum disorder (ASD) refers to a classification of developmental disabilities characterized by changes in social communication, as well as repetitive and restricted patterns of behavior or interests. Approximately 50 percent of ASD risk is linked to genetics and the rest is attributed to environmental factors, including fetal or early childhood exposure to toxic metals and nutrient deficiencies. Researchers from The Senator … Continue reading Infant Teeth Reveal Metal Exposure Correlates with Autism

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The Effects of Insecticidal Nets on Asymptomatic Malaria in India

Caleb Sooknanan ‘20 Over the past decade, mosquitoes have been subject to many vector control strategies in order to control the spread of Malaria. Long-lasting insecticidal nets (LLINs) have been among the most effective, as their distribution has reduced global malaria morbidity by 45% since 2000. However, a large proportion of malarial infections remain asymptomatic, likely preventing malaria elimination programs from being executed to the … Continue reading The Effects of Insecticidal Nets on Asymptomatic Malaria in India

Figure 1: This is an illustration depicting the difference between healthy muscle cells (shown on the right) and muscle cells affected by muscle dystrophy (shown on the left). Due to the degeneration of the muscle cells, they will appear much smaller than usual.

Correcting Muscular Dystrophy Gene Mutations

Richard Liang 18’ Duchenne muscular dystrophy (DMD) is a severe form of muscle degeneration that can become lethal if it affects heart muscle. It is known to be caused by mutations in the X-linked dystrophin-coding gene and thus, there has been ongoing research in correcting these mutations. Currently, there is no effective treatment for this disease. Recently, in a study led by Yu Zhang from … Continue reading Correcting Muscular Dystrophy Gene Mutations