Tag: Neuroscience

2024-25, Cognition, General Neuroscience, Molecular Biology, Neuroscience

Amyloid Burden in WTC Responders: Unraveling the Effects of Air Pollution

Tiffany Ang, Class of 2026 Amyloid-B (AB) proteins, a hallmark of Alzheimer’s disease, have been linked to air pollution exposure, potentially contributing to neurodegenerative diseases. Dr. Kritikos and colleagues at Stony Brook University investigated whether exposure to particulate matter (PM), particularly from the World Trade Center (WTC) site following the 9/11 attacks, was associated with increased cerebral amyloidosis, a condition characterized by the accumulation of … Continue reading Amyloid Burden in WTC Responders: Unraveling the Effects of Air Pollution

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2024-25, Cognition, General Psychology, Neuroscience

An Unfiltered Mind: Why an Overload of Irrelevant Information Causes Hallucinations

Author: Tiffany Ang, Class of 2025 Figure 1: A visual representation of how perception overload amplifies the complexities of cognitive processing. Hallucinations are disruptions in perception that lead to incorrect interpretations of environmental stimuli. Dr. Larsen and colleagues from the Department of Psychology at Stony Brook University are exploring the relationship between hallucination-proneness and the weighting of information, particularly how a diminished responsivity to variations … Continue reading An Unfiltered Mind: Why an Overload of Irrelevant Information Causes Hallucinations

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2024-25, Brain, Degenerative Disease, Disease, mental health, Neuroscience

Amyloid-beta Deposition: A Cause or Byproduct of Alzheimer’s?

Author: Farzad Hoque, Class of 2028 The relationship between neurovascular coupling and Alzheimer’s disease (AD) progression has been a focal point of neurological research. While vascular dysfunction in AD is well-documented, questions remain about whether these abnormalities emerge before amyloid-beta (Aβ) deposition or arise as a consequence. Recent research has shed light on the early neurovascular changes in mouse models of AD, suggesting new mechanisms … Continue reading Amyloid-beta Deposition: A Cause or Byproduct of Alzheimer’s?

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2024-25, Brain, Degenerative Disease, General Neuroscience, Neuroscience

EEG Wave Value Differentiation Explaining Different Stages of Parkinson’s Disease

Author: Ishmam Khan, Class of 2025 Figure: Parkinson’s is a detrimental neurodegenerative disease that affects patients at varying degrees of severity As neurodegenerative diseases like Parkinson’s disease (PD) progress, insights into brain changes become crucial for early diagnoses and effective interventions. In a recent study, Pappalettera et al. at Stony Brook University utilized Approximate Entropy (ApEn) analysis to compare the complex brain signals that occur … Continue reading EEG Wave Value Differentiation Explaining Different Stages of Parkinson’s Disease

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Brain, Degenerative Disease, General Neuroscience

Prolonged Functional Hyperemia Found in Early Stage AD in mouse models

By Asher Agarwal, Class of 2027 When a region of our brain is active, blood vessels dilate to increase blood flow and meet the increased metabolic demand of the area. This is known as functional hyperemia, or neurovascular coupling, and it is critical for maintaining metabolic homeostasis in the brain. Previous research has shown that, in response to novel environments, hippocampal inhibitory interneurons are stimulated … Continue reading Prolonged Functional Hyperemia Found in Early Stage AD in mouse models

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discovery, General, Sociology

Do violent video games desensitize us to real-world violence?

By Asher Agarwal, Class of 2027 Recently, many media sources have been spreading concern that violent video games desensitize players to violence and damage their sense of empathy. Researchers at the University of Vienna and Karolinska Institute in Sweden attempted to test this hypothesis by utilizing fMRI technology. fMRI is a machine that allows one to indirectly measure the activity of the brain as it … Continue reading Do violent video games desensitize us to real-world violence?

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2023-24, 2023-24, Brain, Cellular and Molecular Science, Degenerative Disease, General Neuroscience, Molecular Biology, Neurology, Neuroscience, Year

Mature Oligodendrocytes Demonstrate Delayed Cell Death by Alternate Mechanism

By Vignesh Subramanian, Class of 2024 Figure 1: A myelinating oligodendrocyte in a murine brain.  Oligodendrocytes are specialized glial cells in the central nervous system primarily responsible for myelination, the process of ensheathing the axons of neurons in a lipid-rich membrane known as myelin, which insulates the nerve fibers and speeds up the transmission of the action potentials they conduct. Oligodendrocytes are the products of … Continue reading Mature Oligodendrocytes Demonstrate Delayed Cell Death by Alternate Mechanism

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Biology, Cellular and Molecular Science, Degenerative Disease, discovery, General Neuroscience, Health and Medicine, Neuroscience

Inhibition of Hydrolytic Enzyme May Protect Against Manifestation of AD-Linked Phenotypes

Author: Vignesh Subramanian, Class of 2024 Figure 1: Barnes maze tests were performed to assess the spatial reference memory of the knock-in AD mouse models. Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by significant memory loss and cognitive decline that worsen with age. While the disease’s long-established hallmarks include the aggregation of two misfolded proteins known as beta-amyloid and phosphorylated tau, recent research … Continue reading Inhibition of Hydrolytic Enzyme May Protect Against Manifestation of AD-Linked Phenotypes

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Biology, Brain, General Neuroscience, Health and Medicine

Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

Vignesh Subramanian, Class of 2024 Figure 1: A thrombectomy is a surgical procedure aimed at removing blood clots lodged in an artery of the brain. A stroke is a medical emergency in which blood flow to the brain is disrupted. Strokes may be ischemic (lacking blood supply to brain tissue due to a blocked artery) or hemorrhagic (involving bleeding into the brain tissue due to … Continue reading Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care

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Cellular and Molecular Science, Molecular Biology, Neuroscience

Diminished Glymphatic Transport and Lymphatic Drainage Tied to Cerebral Amyloid Angiopathy

Author: Vignesh Subramanian, Class of 2024 Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder characterized by the accumulation of amyloid protein deposits along cortical capillaries, cerebral vessel walls, and the brain’s leptomeninges. These plaques weaken fragile blood vessels, often resulting in intracerebral hemorrhaging. CAA is linked to vascular cognitive impairment and dysfunction and is a major contributor to the pathogenesis of Alzheimer’s disease (AD) and … Continue reading Diminished Glymphatic Transport and Lymphatic Drainage Tied to Cerebral Amyloid Angiopathy

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Biology, Brain, General Neuroscience, Neuroscience

Humans Remain Behaviorally Responsive to External Auditory Stimuli During Deep Sleep

Author: Vignesh Subramanian, Class of 2024 It has long been assumed that sleep is a stable state of unconsciousness in which an individual cannot perceive and respond to most external stimuli. However, recent studies have indicated that humans can process information, discriminate between basic sensations, and carry out limited executive functions, such as answering yes–no questions, while still asleep. Some oneirological studies have focused on … Continue reading Humans Remain Behaviorally Responsive to External Auditory Stimuli During Deep Sleep

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2023-24, General Neuroscience, General Psychology

Combined Personological and Motivational Correlates Drive Conspiratorial Ideation

Author: Vignesh Subramanian, Class of 2024 Figure 1: Heightened paranoia and feelings of antagonism towards others are among the strongest indicators of conspiratorial ideation. Conspiracy theories are generally unsubstantiated explanations for specific events or circumstances that attribute said events to powerful individuals or groups secretly working in tandem. It remains disputed that either the number of conspiracy theories or the extent of public belief in … Continue reading Combined Personological and Motivational Correlates Drive Conspiratorial Ideation

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